ArticleAmerican journal of human genetics2009
Common variants in the trichohyalin gene are associated with straight hair in Europeans.
Article in American journal of human genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 16 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
139 citing papers in PubMed, 16 syntheses or guidelines pooled it, 266 citations in OpenAlex.
- Loci on chromosome 20 interact with rs16969968 to influence cigarettes per day in European ancestry individuals.Drug and alcohol dependence · 2024Pooled it
- Blood copper and risk of cardiometabolic diseases: a Mendelian randomization study.Human molecular genetics · 2022Pooled it
- Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight.Human molecular genetics · 2021Pooled it
- Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair.Human molecular genetics · 2018Pooled it
- Genome-wide association study of blood lead shows multiple associations near ALAD.Human molecular genetics · 2015Pooled it
- Genome-wide association study identifies loci affecting blood copper, selenium and zinc.Human molecular genetics · 2013Pooled it
- Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect.European journal of human genetics : EJHG · 2013Pooled it
- The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.Addiction biology · 2013Pooled it
- Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions.European journal of human genetics : EJHG · 2013Pooled it
- Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.Nature genetics · 2013Pooled it
- Genome-wide association meta-analysis identifies new endometriosis risk loci.Nature genetics · 2012Pooled it
- Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder.Translational psychiatry · 2012Pooled it
- Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.Molecular psychiatry · 2012Pooled it
- Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.American journal of human genetics · 2012Pooled it
- Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking.Translational psychiatry · 2011Pooled it
- Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.Human molecular genetics · 2011Pooled it
- Undernutrition enhances host attractiveness to mosquitoes and transmission of mosquito-borne diseases.Cell research · 2026Article
- Chromatin Accessibility Reveals Adaptive Regulatory Variation in a Keystone Freshwater Fish.Molecular ecology · 2026Article
- Article
- Patches: A Representation Learning Framework for Decoding Shared and Condition-Specific Transcriptional Programs in Wound Healing.bioRxiv : the preprint server for biology · 2026Article
79 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 2 countries.
Funding
Abstract
Hair morphology is highly differentiated between populations and among people of European ancestry. Whereas hair morphology in East Asian populations has been studied extensively, relatively little is known about the genetics of this trait in Europeans. We performed a genome-wide association scan for hair morphology (straight, wavy, curly) in three Australian samples of European descent. All three samples showed evidence of association implicating the Trichohyalin gene (TCHH), which is expressed in the developing inner root sheath of the hair follicle, and explaining approximately 6% of variance (p=1.5x10(-31)). These variants are at their highest frequency in Northern Europeans, paralleling the distribution of the straight-hair EDAR variant in Asian populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.