ArticleInternational journal of legal medicine2010
Immunohistochemical identification of prevalent right ventricular ischemia causing right heart failure in cases of pulmonary fat embolism.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Fat embolism: a systematic review to facilitate the development of standardised procedures in pathology.Histopathology · 2025Pooled it
- Correlation of pulmonary fat embolism with trauma and resuscitation in children.International journal of legal medicine · 2025Article
- Forensic significance of intracardiac expressions of Nrf2 in acute myocardial ischemia.Scientific reports · 2024Article
- Forensic significance of intracardiac heme oxygenase-1 expression in acute myocardial ischemia.Scientific reports · 2021Article
- Approaching pulmonary fat embolism on postmortem computed tomography.International journal of legal medicine · 2019Article
- Early markers of myocardial ischemia: from the experimental model to forensic pathology cases of sudden cardiac death.International journal of legal medicine · 2018Observational
- Granulomatosis with polyangiitis (Wegener's granulomatosis): a rare variant of sudden natural death.International journal of legal medicine · 2018Article
- Early markers for myocardial ischemia and sudden cardiac death.International journal of legal medicine · 2016Article
- Different degrees of ischaemic injury in the right and left ventricle in cases of severe, nonfatal, pulmonary embolism.International journal of legal medicine · 2015Article
- Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin.International journal of legal medicine · 2012Article
- Sensitivity and specificity of NT-proBNP to detect heart failure at post mortem examination.International journal of legal medicine · 2011Article
- Immunohistochemical expression of fibronectin and C5b-9 in the myocardium in cases of fatal ethanol intoxication.International journal of legal medicine · 2011Article
- Immunohistochemical expression of fibronectin and C5b-9 in the myocardium in cases of carbon monoxide poisoning.International journal of legal medicine · 2011Article
- Correlation of fat embolism severity and subcutaneous fatty tissue crushing and bone fractures.International journal of legal medicine · 2011Article
- Morphological identification of right ventricular failure in cases of fatal pulmonary thromboembolism.International journal of legal medicine · 2011Article
- Massive retroperitoneal haemorrhage after extracorporeal shock wave lithotripsy (ESWL).International journal of legal medicine · 2011Article
- Lethal thyroid storm after uncontrolled intake of liothyronine in order to lose weight.International journal of legal medicine · 2010Article
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5 authors.
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Abstract
Pulmonary fat embolism is a life-threatening event that may result to potentially determining right ventricular failure. Even if the pathophysiology of this phenomenon has been widely investigated, no immunohistochemical demonstration of right ventricular failure following pulmonary fat embolism has been reported till now. We performed an immunohistochemical investigation with the markers fibronectin and C5b-9 in 21 cases of polytrauma with bone fractures (study group-nine females and 12 males; mean age 64.6 years) compared to a control group of 21 forensic cases with various causes of death (nine females and 12 males; mean age 68.6 years). In each case at least one tissue slide from both cardiac ventricles (free wall of the right ventricle, anterior and/or posterior wall of the left ventricle) was available. The reactions were semi-quantitatively classified, and the two groups were compared. In the study group, the occurrence of ischemic changes at the right ventricle was significantly higher than in controls. The determining aspect, however, seems to be the prevalent ischemic lesion at the right ventricle compared to the left one. This may indicate the primary involvement of the right ventricle, thus, demonstrating a right ventricular failure.
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