ArticleClinics in laboratory medicine2009
Respiratory viruses in bronchiolitis and their link to recurrent wheezing and asthma.
Article in Clinics in laboratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Study Measuring Exhaled Nitric Oxide Levels in Infants and Young Children Admitted to the Hospital for Respiratory Syncytial Virus (RSV) or Other Viral Lower Respiratory Tract Infections
Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy, Safety and Tolerability of ORal Bacterial EXtract for the Prevention of Wheezing Lower Respiratory Tract Illness (ORBEX)
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A systematic review of predictive models for asthma development in children.BMC medical informatics and decision making · 2015Pooled it
- Trial
- Selective Blockade of TNFR1 Improves Clinical Disease and Bronchoconstriction in Experimental RSV Infection.Viruses · 2020Article
- The prevalence of human bocavirus in <2-year-old children with acute bronchiolitis.New microbes and new infections · 2020Review
- Innate IFN-lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2020Article
- Bedside clinical assessment predicts recurrence after hospitalization due to viral lower respiratory tract infection in young children.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020Article
- Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways.The Journal of infectious diseases · 2018Article
- Bronchiolitis in young infants: is it a risk factor for recurrent wheezing in childhood?World journal of pediatrics : WJP · 2017Article
- Vitamin D Status in Infants with Two Different Wheezing Phenotypes.Indian journal of pediatrics · 2016Article
- Low serum 25-hydroxyvitamin D levels and bronchiolitis severity in Spanish infants.European journal of pediatrics · 2015Article
- MLBCD: a machine learning tool for big clinical data.Health information science and systems · 2015Article
- Recurrent wheezing 36 months after bronchiolitis is associated with rhinovirus infections and blood eosinophilia.Acta paediatrica (Oslo, Norway : 1992) · 2014Article
- Respiratory morbidity of preterm infants of less than 33 weeks gestation without bronchopulmonary dysplasia: a 12-month follow-up of the CASTOR study cohort.Epidemiology and infection · 2014Article
- Article
- Environmental factors association between asthma and acute bronchiolitis in young children--a perspective cohort study.European journal of pediatrics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Bronchiolitis is the leading cause of hospitalization for children younger than 1 year of age and these hospitalized children have an increased risk for developing childhood asthma. It remains unclear, however, which children who have severe bronchiolitis (eg, an episode requiring hospitalization) will develop recurrent wheezing or asthma. Although many environmental and genetic factors may play a role in the pathway from bronchiolitis to asthma, this article focuses on the viruses that have been linked to bronchiolitis and how these viruses may predict or contribute to future wheezing and asthma. The article also discusses vitamin D as an emerging risk factor for respiratory infections and wheezing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.