Evidence map›Paper›PMID 19892227›Full record

ReviewClinics in laboratory medicine2009

Utilization of nucleic acid amplification assays for the detection of respiratory viruses.

Sue C Kehl, Swati Kumar

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in laboratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Evaluation of Anyplex™ II RV16 and RB5 real-time RT-PCR compared to SeeplexJournal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2017
    Article
  6. Article
  7. Article
  8. An unusual case of influenza-like illness after yellow fever vaccination.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Use and evaluation of molecular diagnostics for pneumonia etiology studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012
    Review
  14. Article
  15. Article
  16. Review
  17. Diagnosis of respiratory syncytial virus infection.The open microbiology journal · 2011
    Article
  18. Article
  19. Viral detection profile in children with severe acute respiratory infection.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sue C KehlDepartment of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226-0509, USA. kskehl@mcw.edu
Swati Kumar
Medical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses are major contributors to morbidity and mortality from acute respiratory infections in all age groups worldwide. Accurate identification of the etiologic agent of respiratory tract infections is important for proper patient management. Diagnosis can be problematic, because a range of potential pathogens can cause similar clinical symptoms. Nucleic acid amplification testing is emerging as the preferred method of diagnostic testing. Real-time technology and the ability to perform multiplex testing have facilitated this emergence. Commercial platforms for nucleic acid amplification testing of respiratory viruses include real-time polymerase chain reaction (PCR), nucleic acid sequence-based amplification, and loop-mediated isothermal amplification. Multiplex PCR with fluidic microarrays or DNA chips are the most recent diagnostic advance. These assays offer significant advantages in sensitivity over antigen detection methods and in most cases also over traditional culture methods. A limited number of assays, however, are commercially available, thus laboratory developed assays frequently are used. This article reviews the performance of commercially available assays and discusses issues relevant to the development of in-house assays.

Indexed as

Nucleic Acid Amplification TechniquesAdenoviridaeDNA, ViralHumansMetapneumovirusOrthomyxoviridaeRespiratory Syncytial Virus, HumanRespiratory Tract InfectionsRespirovirusRNA, ViralDNA, ViralRNA, Viral

Identifiers

PMID19892227
PMCPMC7131773
OpenAlexW1985251368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.