Evidence map›Paper›PMID 19892224›Full record

ReviewClinics in laboratory medicine2009

Developments in tissue culture detection of respiratory viruses.

Alexander J McAdam, Ann Marie Riley

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in laboratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alexander J McAdamDepartment of Pathology, Harvard Medical School, Boston, MA 02115, USA. Alexander.McAdam@childrens.harvard.edu
Ann Marie Riley
Boston Children's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral culture is the historical gold standard for detection of most viruses that cause respiratory tract infections. Viral culture remains valuable because it is reasonably sensitive for most respiratory viruses, and it is cheaper and less technically demanding than nucleic acid amplified tests. The disadvantages of conventional viral culture using multiple tubes of cell lines are that it is labor intensive, moderately expensive, and slow. Advances in viral culture include the introduction of new cell lines, which can be more sensitive or convenient than previously used cell lines, and the use of shell-vial culture for respiratory viruses. Shell-vial culture is as sensitive as conventional culture for most respiratory viruses and it has a much shorter turn-around time. The shorter turn-around time increases the clinical utility of these cultures.

Indexed as

AnimalsCell LineDogsHumansNucleic Acid Amplification TechniquesRespiratory Tract InfectionsVirus CultivationViruses

Identifiers

PMID19892224
PMCPMC7131767
OpenAlexW2063729432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.