Evidence map›Paper›PMID 19892211›Full record

ArticleGeneral hospital psychiatry

Psychiatric management of HIV/HCV-coinfected patients beginning treatment for hepatitis C virus infection: survey of provider practices.

Jeffrey J Weiss, Susan Morgello

Abstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeffrey J WeissDepartment of Psychiatry, Mount Sinai School of Medicine, Box 1228, New York, NY 10029, USA. jeffrey.weiss@msnyuhealth.org
Susan Morgello
Icahn School of Medicine at Mount Sinai · US

Funding

Adherence to HCV Treatment in HCV and HCV/HIV PatientsK23MH071177 · NIMH · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI WEISS, JEFFREY J · 2005 to 2009
$730k
NIMH NIH HHS K23 MH071177NIMH NIH HHS K23MH071177
6 · The paper itself

Abstract

objectiveTo determine expert clinical practice in the management of psychiatric status of HIV/hepatitis C virus (HCV)-coinfected patients initiating pegylated interferon/ribavirin for the treatment of hepatitis C.

methodTwo hundred thirty-six expert providers were identified and invited by email to complete an online anonymous survey.

resultsNinety-two providers (39%) completed the survey, 24 (26%) of whom are psychiatrists. More than one third of providers indicate that they use or offer the option of antidepressant use prophylactically in HIV-positive patients with no past or current depression beginning HCV treatment, and more than three quarters do so in patients with a history of depression but no current symptoms of depression. The most experienced nonpsychiatrist providers were more likely to use antidepressants prior to the start of treatment in HIV-coinfected patients as compared to in HCV monoinfected patients. There is consensus among providers to leave psychiatric medication unchanged in patients currently treated for unipolar depression.

conclusionsMany expert providers prescribe antidepressants to HIV/HCV-coinfected patients initiating Hepatitis C treatment in the absence of symptoms of depression, despite the lack of data supporting this approach in this population. Research is needed to provide an evidence base to guide the optimal psychiatric management of HIV/HCV-coinfected patients beginning hepatitis C treatment.

Indexed as

Evidence-Based MedicineAdultAIDS-Related Opportunistic InfectionsAntidepressive AgentsAntiviral AgentsComorbidityDepressive DisorderFemaleHealth Services ResearchHealth SurveysHepatitis C, ChronicHIV InfectionsHumansInterferon-alphaInterferon alpha-2MaleAntidepressive AgentsAntiviral AgentsInterferon-alphaInterferon alpha-2peginterferon alfa-2aPolyethylene GlycolsRecombinant ProteinsRibavirin

Identifiers

PMID19892211
PMCPMC2788966
OpenAlexW2138618194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.