Evidence map›Paper›PMID 19890744›Full record

ArticleWiener klinische Wochenschrift2009

Analysis of Slovenian MRSA strains with susceptibility patterns suggestive of CA-MRSA.

Irena Grmek-Kosnik, Urska Dermota, Helena Ribic, Mateja Ravnik, Martina Kavcic, Tatjana Harlander, Tjasa Zohar-Cretnik, Iztok Strumbelj, Ljudmila Sarjanovic, Alenka Kraigher

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Wiener klinische Wochenschrift, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. COPD is not COPD is not allergy.Wiener klinische Wochenschrift · 2009
    Article
  5. Community-associated MRSA - the forthcoming epidemic?Wiener klinische Wochenschrift · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Irena Grmek-KosnikInstitute of Public Health Kranj, Kranj, Slovenia. irena.grmek-kosnik@zzv-kr.si
Urska Dermota
Helena Ribic
Mateja Ravnik
Martina Kavcic
Tatjana Harlander
Tjasa Zohar-Cretnik
Iztok Strumbelj
Ljudmila Sarjanovic
Alenka Kraigher

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommunity-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) differs from healthcare-associated MRSA (HA-MRSA) in its molecular and microbiological characteristics. MATERIALS AND

methodsSix Slovenian regional public health institutes and the National Institute of Public Health took part in monitoring CA-MRSA infections. S. aureus isolates resistant to oxacillin and susceptible to > or = two of the four antibiotics ciprofloxacin, erythromycin, clindamycin or gentamicin were defined as CA-MRSA and further analyzed. The presence of the gene for Panton-Valentine leukocidin (PVL) was confirmed using PCR, the type of staphylococcal cassette chromosome (SCCmec) using multiplex PCR, and macrorestriction analysis of chromosomal DNA using pulsed-field gel electrophoresis (PFGE).

resultsA total of 31 strains from 31 patients were analyzed during a period of 21 months: 23 specimens were sent from hospitals, six from primary care, two from a long-term care facility. All 31 isolates contained the gene mecA. Sixteen (51.6%) isolates were identified as SCCmec type IV, three isolates were PVL positive. Using PFGE, the CA-MRSA strains were classified into 15 similarity groups. Results of antibiotic susceptibility showed there were five resistance types among the 31 strains. Simultaneous resistance against ciprofloxacin and gentamicin was often associated with the presence of SCCmec type I, strongly resembling HA-MRSA.

conclusionsPVL-positive strains of CA-MRSA have been isolated in Slovenia only rarely. We will continue to monitor strains of MRSA in order to obtain the complete microbiological and epidemiological features.

Indexed as

Community-Acquired InfectionsDisease SusceptibilityHumansMethicillin-Resistant Staphylococcus aureusSloveniaStaphylococcal Infections

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.