ReviewJournal of the Royal Society, Interface2010
Biological nano-functionalization of titanium-based biomaterial surfaces: a flexible toolbox.
Review in Journal of the Royal Society, Interface, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed.
- A narrative review of recent developments in osseointegration and anti-corrosion of titanium dental implants with nano surface.Bone reports · 2025Review
- The Use of Vacuum Plasma Surface Treatment to Improve the Hydrophilicity and Wettability of Bone Graft Substitutes and Resorbable Membranes: An In Vitro Study.Dentistry journal · 2025Article
- Advanced Strategies for Enhancing the Biocompatibility and Antibacterial Properties of Implantable Structures.Materials (Basel, Switzerland) · 2025Review
- Review
- Nanomolecularly-induced Effects at Titania/Organo-Diphosphonate Interfaces for Stable Hybrid Multilayers with Emergent Properties.ACS applied nano materials · 2024Article
- Mn-doped Ti-based MOFs for magnetic resonance imaging-guided synergistic microwave thermal and microwave dynamic therapy of liver cancer.Bioactive materials · 2023Article
- Human Histological Analysis of Early Bone Response to Immediately Loaded Narrow Dental Implants with Biphasic Calcium PhosphateDentistry journal · 2023Article
- Electrode Potential-Dependent Studies of Protein Adsorption on TiMolecules (Basel, Switzerland) · 2023Article
- Proteolytically Resistant Bioactive Peptide-Grafted Sr/Mg-Doped Hardystonite Foams: Comparison of Two Covalent Functionalization Strategies.Biomimetics (Basel, Switzerland) · 2023Article
- Effects of rmBMP-7 on Osteoblastic Cells Grown on a Nanostructured Titanium Surface.Biomimetics (Basel, Switzerland) · 2022Article
- A Nanoindentation Approach for Time-Dependent Evaluation of Surface Free Energy in Micro- and Nano-Structured Titanium.Materials (Basel, Switzerland) · 2021Article
- Interaction of KRSR Peptide with Titanium Dioxide Anatase (100) Surface: A Molecular Dynamics Simulation Study.International journal of molecular sciences · 2021Article
- Article
- Osteogenic effects of microRNA-335-5p/lipidoid nanoparticles coated on titanium surface.Archives of oral biology · 2021Article
- Biochemical Modification of Titanium Oral Implants: Evidence from In Vivo Studies.Materials (Basel, Switzerland) · 2021Review
- Article
- TETT-functionalized TiONanoscale advances · 2020Article
- Dendritic Scaffold onto Titanium Implants. A Versatile Strategy Increasing Biocompatibility.Polymers · 2020Article
- Microarc oxidation surface of titanium implants promote osteogenic differentiation by activating ERK1/2-miR-1827-Osterix.In vitro cellular & developmental biology. Animal · 2020Article
- Dental Implants with Anti-Biofilm Properties: A Pilot Study for Developing a New Sericin-Based Coating.Materials (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surface functionalization with bioactive molecules (BAMs) on a nanometre scale is a main field in current biomaterial research. The immobilization of a vast number of substances and molecules, ranging from inorganic calcium phosphate phases up to peptides and proteins, has been investigated throughout recent decades. However, in vitro and in vivo results are heterogeneous. This may be at least partially attributed to the limits of the applied immobilization methods. Therefore, this paper highlights, in the first part, advantages and limits of the currently applied methods for the biological nano-functionalization of titanium-based biomaterial surfaces. The second part describes a new immobilization system recently developed in our groups. It uses the nanomechanical fixation of at least partially single-stranded nucleic acids (NAs) into an anodic titanium oxide layer as an immobilization principle and their hybridization ability for the functionalization of the surface with BAMs conjugated to the respective complementary NA strands.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.