Trial reportJournal of cardiothoracic surgery2009
Efficacy of TachoSil patches in controlling Dacron suture-hole bleeding after abdominal aortic aneurysm open repair.
Trial report in Journal of cardiothoracic surgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- The role of sealants for achieving anastomotic hemostasis in vascular surgery.The Cochrane database of systematic reviews · 2024Pooled it
- Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2023Pooled it
- Economic and outcomes consequences of TachoSil®: a systematic review.Vascular health and risk management · 2014Pooled it
- Collagen sealant patch to reduce lymphatic drainage after lymph node dissection.World journal of surgical oncology · 2012Trial
- Could TachoSil application in cardiac surgery be potentially dangerous? A review of the literature.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025Review
- Electrospun PCL-Based Vascular Grafts: In Vitro Tests.Nanomaterials (Basel, Switzerland) · 2021Article
- Anastomotic sealing with a fibrin-coated collagen patch in small-diameter bowel.Langenbeck's archives of surgery · 2011Article
- From surgery to neurosurgery: our experience on the efficacy of fleece-bound sealing (TachoSil®) for dural repair.Il Giornale di chirurgiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is evaluate the efficacy of TachoSil patches in controlling suture-hole bleeding after elective infrarenal abdominal aortic aneurysm (AAA) replacement with Dacron graft. MATERIALS AND
methodsPatients undergoing elective replacement of infrarenal AAA with Dacron grafts were prospectively randomized to TachoSil patches (Group I) or standard compression with surgical swabs (Group II).We evaluated time to haemostasis, blood loss during the operation, blood loss after cross-clamp removal, duration of operation, drain volume, requirement for blood transfusion and surgeons rating of efficacy.
resultsTwenty patients were randomized (10 patients in each treatment Group). The mean time to haemostasis was 264 +/- 127.1 s (range: 180-600 s) in Group I and 408 +/- 159.5 s (range: 120-720 s) in Group II (p = 0.026); mean blood loss during the operation was 503.5 +/- 20.7 cc (range: 474-545 cc) in Group I and 615.7 +/- 60.3 cc (range: 530-720 cc) in Group II (p < 0.001); mean blood loss after cross-clamp removal was 26.5 +/- 4 g (range: 22-34 g) in Group I and 45.4 +/- 4.6 (range: 38-52 g) in Group II (p < 0.001) and mean drain volume was 116.7 +/- 41.4 cc (range: 79-230 cc) in Group I and 134.5 +/- 42.8 cc (range: 101-250 cc) in Group II (p = 0.034). There were no serious adverse events associated with use of TachoSil patches.
conclusionFor patients undergoing aortic reconstruction with Dacron grafts, TachoSil patches were found to be safe and effective for the control of suture-hole bleeding.
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Registered trials
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