ArticleJournal of diabetes science and technology2007
Electrical stimulation as treatment for obesity and diabetes.
Article in Journal of diabetes science and technology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Artificial Neural Network-Based Automatic Detection of Food Intake for Neuromodulation in Treating Obesity and Diabetes.Obesity surgery · 2020Article
- The Role of Minimally Invasive and Endoscopic Technologies in Morbid Obesity Treatment: Review and Critical Appraisal of the Current Clinical Practice.Obesity surgery · 2020Review
- Closed-loop bioelectronic medicine for diabetes management.Bioelectronic medicine · 2020Review
- Vagus Nerve Stimulation in Rodent Models: An Overview of Technical Considerations.Frontiers in neuroscience · 2019Review
- Neuromodulation of metabolic functions: from pharmaceuticals to bioelectronics to biocircuits.Journal of biological engineering · 2019Review
- Clinically indicated electrical stimulation strategies to treat patients with medically refractory epilepsy.Epilepsia open · 2018Article
- The role of proximal versus distal stomach resection in the weight loss seen after vertical sleeve gastrectomy.American journal of physiology. Regulatory, integrative and comparative physiology · 2016Article
- Interventional treatment of obesity and diabetes: An interim report on gastric electrical stimulation.Reviews in endocrine & metabolic disorders · 2016Review
- A pilot study to compare meal-triggered gastric electrical stimulation and insulin treatment in Chinese obese type 2 diabetes.Diabetes technology & therapeutics · 2015Article
- Updates on gastric electrical stimulation to treat obesity: Systematic review and future perspectives.World journal of gastrointestinal endoscopy · 2014Article
- Fasting plasma triglycerides predict the glycaemic response to treatment of type 2 diabetes by gastric electrical stimulation. A novel lipotoxicity paradigm.Diabetic medicine : a journal of the British Diabetic Association · 2013Article
- Gastric electrical stimulation for the treatment of obesity: from entrainment to bezoars-a functional review.ISRN gastroenterology · 2013Article
- Gastric stimulation for weight loss.World journal of gastroenterology · 2012Review
- A pilot study to evaluate the effect of splanchnic nerve stimulation on body composition and food intake in rats.Obesity surgery · 2009Article
- Stimulation of sympathetic innervation in the upper gastrointestinal tract as a treatment for obesity.Medical hypotheses · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of obesity is growing, is driving an increase in the prevalence of diabetes, and is creating a major public health crisis in the United States. Lifestyle and behavior therapy rarely give durable weight loss. There are few medications approved for the treatment of obesity. Those that exist are limited in efficacy and using them in combination does not result in greater weight loss. Surgical treatments for obesity are effective and give durable weight loss, but are accompanied by measurable morbidity and mortality. Several pacing approaches are being tried and are an outgrowth of pacing for gastroparesis. The Transcend(R) pacemaker blocks vagal efferents and delays gastric emptying, giving a 40% loss of excess body weight, if certain screening procedures are employed. The Tantulus pacemaker is still in development but increases antral muscular contractions and delays gastric emptying by stimulation during the absolute refractory period. Weight loss has been 30% of excess body weight, and glycohemoglobin decreased 1.6% in a trial of obese type 2 diabetes. Stimulation to the subdiaphragmatic sympathetics, vagal nerve stimulation with or without unilateral vagotomy, and intestinal pacing are other approaches that are still being evaluated preclinically. Clearly a safe, effective, and durable treatment for obesity is desperately needed. Electrical pacing of the gastrointestinal tract is promising therapeutically, and because pacemakers work through different mechanisms, combining pacemaker treatments may be possible. Rapid progress is being made in the field of electrical stimulation as a treatment for obesity and even greater progress can be expected in the foreseeable future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.