ArticlePloS one2009
Aspergillus terreus accessory conidia are unique in surface architecture, cell wall composition and germination kinetics.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Strategic utilization of chicken bones immobilized by Aspergillus terreus for sustainable bioremediation of cobalt: statistical modeling, kinetics and thermodynamic studies.Journal of biological engineering · 2026Article
- A new model for the global patterning of spores and pollen grains.Protoplasma · 2026Article
- Accelerating the understanding ofCurrent research in microbial sciences · 2024Review
- The Novel Monoclonal IgGJournal of fungi (Basel, Switzerland) · 2023Article
- Bovine abortion and necrotic placentitis by Aspergillus terreus.The Journal of veterinary medical science · 2022Article
- A retrospective multi-center study of treatment, outcome, and prognostic factors in 34 dogs with disseminated aspergillosis in Australia.Journal of veterinary internal medicine · 2022Article
- Characterization ofFrontiers in microbiology · 2022Article
- Cryptic species ofVirulence · 2019Article
- Resistance mechanism and proteins inMycology · 2019Review
- Article
- InvasiveInfection and drug resistance · 2017Article
- Hide, Keep Quiet, and Keep Low: Properties That Make Aspergillus fumigatus a Successful Lung Pathogen.Frontiers in microbiology · 2016Article
- Aspergillus terreus infection in a sutureless self-sealing incision made during cataract surgery.Mycopathologia · 2015Article
- Invasion of Solanum tuberosum L. by Aspergillus terreus: a microscopic and proteomics insight on pathogenicity.BMC research notes · 2014Article
- Phylogeny, identification and nomenclature of the genus Aspergillus.Studies in mycology · 2014Article
- Virulence and thrombocyte affectation of two Aspergillus terreus isolates differing in amphotericin B susceptibility.Medical microbiology and immunology · 2013Article
- New insight into amphotericin B resistance in Aspergillus terreus.Antimicrobial agents and chemotherapy · 2013Article
- Invasive aspergillosis: resistance to antifungal drugs.Mycopathologia · 2012Review
- Article
- The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus.PloS one · 2012Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection with Aspergillus terreus is more likely to result in invasive, disseminated disease when compared to other Aspergillus species; importantly this species appears to be less susceptible to the antifungal drug amphotericin B. Unique to this species is the ability to produce specialized structures denoted as accessory conidia (AC) directly on hyphae both in vitro and in vivo. With the hypothesis that production of AC by A. terreus may enhance virulence of this organism, we analyzed the phenotype, structure and metabolic potential of these conidia. Comparison of A. terreus phialidic conidia (conidia that arise from conidiophores, PC) and AC architecture by electron microscopy revealed distinct morphological differences between the two conidial forms; AC have a smoother, thicker outer cell surface with no apparent pigment-like layer. Further, AC germinated rapidly, had enhanced adherence to microspheres, and were metabolically more active compared to PC. Additionally, AC contained less cell membrane ergosterol, which correlated with decreased susceptibility to AMB as determined using a flow cytometry based analysis. Furthermore, AC exhibited surface patches of beta1-3 glucan, suggestive of attachment scarring. Collectively, the findings of this study suggest a possible role for AC in A. terreus pathogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.