ArticleComparative medicine2009
MRI features in a canine model of ischemic stroke: correlation between lesion volume and neurobehavioral status during the subacute stage.
Article in Comparative medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Behavioral tests to assess short- and long-lasting sensorimotor deficits following transient focal cerebral ischemia in rodents.Pharmacological reports : PR · 2025Review
- Convergence Retraction Nystagmus Secondary to Central Nervous System Disseminated Coccidioides Immitis Infection in a Dog.Veterinary medicine and science · 2025Article
- Article
- Temporal and sequence-related variability in diffusion-weighted imaging of presumed cerebrovascular accidents in the dog brain.Frontiers in veterinary science · 2022Article
- Large animal ischemic stroke models: replicating human stroke pathophysiology.Neural regeneration research · 2020Review
- Infarct Evolution in a Large Animal Model of Middle Cerebral Artery Occlusion.Translational stroke research · 2020Article
- Imaging Ischemic and Hemorrhagic Disease of the Brain in Dogs.Frontiers in veterinary science · 2020Review
- Diffusion-Weighted Imaging Findings of Ischemic Spinal Injury in a Chondrodystrophic Dog With Fibrocartilaginous Embolism.Frontiers in veterinary science · 2020Article
- Magnetic resonance imaging characteristics of ischemic brain infarction over time in a canine stroke model.Journal of veterinary science · 2018Article
- Translational models for vascular cognitive impairment: a review including larger species.BMC medicine · 2017Review
- Canine model of ischemic stroke with permanent middle cerebral artery occlusion: clinical features, magnetic resonance imaging, histopathology, and immunohistochemistry.Journal of veterinary science · 2015Article
- In vivo MR imaging of intraarterially delivered magnetically labeled mesenchymal stem cells in a canine stroke model.PloS one · 2013Article
- Histopathological Investigation of Different MCAO Modalities and Impact of Autologous Bone Marrow Mononuclear Cell Administration in an Ovine Stroke Model.Translational stroke research · 2011Article
- Correlating magnetic resonance findings with neuropathology and clinical signs in dogs and cats.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology AssociationArticle
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to evaluate the diagnostic value of magnetic resonance imaging (MRI) and assess the correlation between the volume of the ischemic lesion and neurobehavioral status during the subacute stage of ischemic stroke. Ischemic stroke was induced in 6 healthy laboratory beagles through permanent occlusion of the middle cerebral artery (MCAO). T2-weighted and fluid-attenuated inversion recovery (FLAIR) imaging, diffusion-weighted imaging (DWI), measurement of the apparent diffusion coefficient (ADC) ratio, and neurobehavioral evaluation were performed 3 times serially by using a 1.5-T MR system: before and 3 and 10 d after MCAO. Ischemic lesions demonstrated T2 hyperintensity, FLAIR hyperintensity, and DWI hyperintensity. The ADC ratio was decreased initially but then was increased at 10 d after MCAO. Ischemic lesion volumes on T2-weighted and FLAIR imaging were not significantly different from those on DWI. The lesion volume and neurobehavioral score showed strong correlation. Our results suggest that conventional MRI may be a reliable diagnostic tool during the subacute stage of canine ischemic stroke.
Indexed as
Identifiers
19887030PMC2771604W2172687817What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.