Evidence map›Paper›PMID 19885685›Full record

ReviewPediatric nephrology (Berlin, Germany)2010

Small vessel vasculitis.

Paul Brogan, Despina Eleftheriou, Michael Dillon

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Intramedullary lesion resection as an effective treatment of spinal cord microscopic polyangiitis: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  9. Article
  10. Article
  11. Vasculitis update: pathogenesis and biomarkers.Pediatric nephrology (Berlin, Germany) · 2018
    Review
  12. Article
  13. Article
  14. Pediatric Vasculitis.Indian journal of pediatrics · 2016
    Review
  15. Article
  16. Henoch-Schönlein purpura with hypocomplementemia.Pediatric nephrology (Berlin, Germany) · 2012
    Article
  17. Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticles.Journal of the American Society of Nephrology : JASN · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Paul BroganDepartment of Rheumatology, Institute of Child Health, 30 Guilford St, London, WC1N1EH, UK. p.brogan@ich.ucl.ac.uk
Despina Eleftheriou
Michael Dillon
Institute of Child Health · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pediatric small vessel vasculitides reviewed in this article are Henoch-Schönlein purpura (HSP) and the anti-neutrophil cytoplasmic antibody-associated vasculitides (AAV). The new classification criteria for HSP and Wegener's granulomatosis are now validated and will facilitate the conduct of future epidemiological studies and clinical trials. The clinical manifestations of small vessel vasculitis in children are described, and current therapies discussed. There is a lack of good clinical trial data on which to base therapy for HSP. Similarly, data based on randomized controlled trials (RCTs) for pediatric AAV are lacking, although children with AAV are for the first time now included in a RCT of mycophenolate mofetil versus cyclophosphamide. Significant challenges remain in the field of pediatric small vessel vasculitis, including the development of validated disease outcome measures and biomarkers to be used in clinical trials. Lastly, long-term outcome data are lacking in survivors of pediatric small vessel vasculitis.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisChildClinical Trials as TopicHumansIgA Vasculitis

Identifiers

PMID19885685
PMCPMC2855433
OpenAlexW2096862703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.