ReviewPediatric nephrology (Berlin, Germany)2010
Bone disease and hypercalciuria in children.
Review in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Investigating the Prevalence of Hypercalciuria in Children Aged 2-16 Years With Asymptomatic Microscopic Hematuria in 2020 in Tehran Children's Medical Center.Clinical case reports · 2024Article
- Effect of Vitamin D Treatment on Dynamics of Stones Formation in the Urinary Tract and Bone Density in Children with Idiopathic Hypercalciuria.Nutrients · 2020Article
- Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones.Pediatric nephrology (Berlin, Germany) · 2020Review
- Does idiopathic hypercalciuria affect bone metabolism during childhood? A prospective case-control study.Pediatric nephrology (Berlin, Germany) · 2018Article
- The value of hypercalciuria in patients with osteopenia versus osteoporosis.Urolithiasis · 2017Article
- Random urinary calcium/creatinine ratio for screening hypercalciuria in children with hematuria.Annals of laboratory medicine · 2013Article
- Oral health care in children with haemophilia in Helsinki, Finland.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2013Article
- Plasma and urinary levels of cytokines in patients with idiopathic hypercalciuria.Pediatric nephrology (Berlin, Germany) · 2012Article
- Effect of thiazides on bone mineral density in children with idiopathic hypercalciuria.Pediatric nephrology (Berlin, Germany) · 2012Article
- Approach to the child with fractures.The Journal of clinical endocrinology and metabolism · 2011Article
- Epidemiology of pediatric urolithiasis.Indian journal of urology : IJU : journal of the Urological Society of India · 2010Article
- Neurofibromatosis type 1 with idiopathic hypercalciuria, nephrolithiasis and horseshoe kidney.Pediatric nephrology (Berlin, Germany) · 2010Article
- The impact of vitamin D supplementation on vitamin D level, urinary calcium excretion and bone density in patients with hypercalciuria and vitamin D deficiency - preliminary report.Developmental period medicineArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There have been relatively few studies of bone mass in children with idiopathic hypercalciuria (IH). When performed, bone mineral density (BMD) measurements have consistently disclosed decreased Z-scores for children with IH at the lumbar spine and, to a lesser extent, at the femoral neck. Few investigations have delineated the nature of the mechanism(s) that may contribute to the bone loss in these children. Some studies have been consistent, showing increased bone resorption as the probable mechanism of bone loss. To date, there have been no reports regarding the assessment of biochemical markers specific for bone formation in children with IH. However, since most of the children with IH in these reports had demonstrated normal longitudinal growth, it seems less likely that there is an alteration in bone formation. The causes for increased bone resorption also are not firmly established, but genetics, dietary indiscretions, and altered cytokine production have been proposed as being contributory to the decreased BMD observed in these children with IH. Optimal bone mineral accretion during childhood and adolescence is important in attaining peak bone mass and may serve to prevent the development of osteoporosis in adulthood. Thus, a better understanding of bone loss in children with IH is warranted.
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