ArticleKorean journal of radiology
Changes in muscular lipids in unilateral isolated hypertrophy of gastrocnemius muscle can be revealed by 1H MR spectroscopy.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo test whether proton magnetic resonance spectroscopy ((1)H-MRS) reveals changes in the lipid content of the gastrocnemius muscle (GM) and soleus muscle (SOL) of a patient with unilateral isolated hypertrophy of the right GM. MATERIALS AND
methods(1)H-MRS was performed on a 1.5 Tesla (T) whole-body unit. Muscular lipids inside SOL and GM were assessed in both calves of the patient by a STEAM (stimulated echo acquisition mode) localization sequence. Results were compared to a control group of four healthy volunteers.
resultsTotal amount of muscular lipids in the hypertrophic GM of the patient was clearly increased compared to the controls (38.7 versus 21.8+/-3.5 a.u.) while intramyocellular lipids of the adjacent SOL were lower compared to the contralateral healthy leg.
conclusionMuscular lipids are substrates for metabolism and can be assessed non-invasively by (1)H-MRS. (1)H-MRS is considered to be a helpful tool in clinical assessment of muscle metabolism in cases with muscular hypo- or hypertrophy.
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