ArticleAntimicrobial agents and chemotherapy2010
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Article
- Article
- Antimicrobial Resistance in Romania: Updates on Gram-Negative ESCAPE Pathogens in the Clinical, Veterinary, and Aquatic Sectors.International journal of molecular sciences · 2023Review
- Characterization of multidrug-resistant and virulent Klebsiella pneumoniae strains belonging to the high-risk clonal group 258 (CG258) isolated from inpatients in northeastern Brazil.Archives of microbiology · 2021Article
- Integrase-Mediated Recombination of theAntimicrobial agents and chemotherapy · 2018Article
- Detection of β-lactamase encoding genes in feces, soil and water from a Brazilian pig farm.Environmental monitoring and assessment · 2018Article
- Colonization of long-term care facility residents in three Italian Provinces by multidrug-resistant bacteria.Antimicrobial resistance and infection control · 2018Article
- Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and Its Complexes with Moxalactam and Imipenem.Antimicrobial agents and chemotherapy · 2016Article
- A novel extended-spectrum β-lactamase, SGM-1, from an environmental isolate of Sphingobium sp.Antimicrobial agents and chemotherapy · 2013Article
- Detection of P. aeruginosa harboring bla CTX-M-2, bla GES-1 and bla GES-5, bla IMP-1 and bla SPM-1 causing infections in Brazilian tertiary-care hospital.BMC infectious diseases · 2012Article
- The class A β-lactamase FTU-1 is native to Francisella tularensis.Antimicrobial agents and chemotherapy · 2012Article
- Pseudomonas aeruginosa: resistance to the max.Frontiers in microbiology · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A Pseudomonas aeruginosa isolate recovered in Belgium produced a novel extended-spectrum ss-lactamase, BEL-2, differing from BEL-1 by a single Leu162Phe substitution. That modification significantly altered the kinetic properties of the enzyme, increasing its affinity for expanded-spectrum cephalosporins. The bla(BEL-2) gene was identified from a P. aeruginosa isolate clonally related to another bla(BEL-1)-positive isolate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.