ArticleIndian journal of dermatology2008
Unraveling the mystery of vernix caseosa.
Article in Indian journal of dermatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05425394 (A Study of Effects of Delay in the First Bathing Time of Newborns on the Rate of Body Temperature and the Rate of Exclusive Breastfeeding), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study of Effects of Delay in the First Bathing Time of Newborns on the Rate of Body Temperature and the Rate of Exclusive Breastfeeding: A Randomized Controlled Trial
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevention and Treatment of Neonatal Infections in Facility and Community Settings of Low- and Middle-Income Countries: A Descriptive Review.Neonatology · 2025Pooled it
- Timing of first bath in term healthy newborns: A systematic review.Journal of global health · 2022Pooled it
- Newborn's first bath: any preferred timing? A pilot study from Lebanon.BMC research notes · 2020Trial
- "We have to clean ourselves to ensure that our children are healthy and beautiful": findings from a qualitative assessment of a hand hygiene poster in rural Uganda.BMC public health · 2019Trial
- Factors associated with delayed neonatal bathing in Afghanistan: insights from the 2022-2023 multiple indicator cluster survey.BMC research notes · 2025Article
- The role of medical imaging in the management of vernix caseosa peritonitis: A case report.Radiology case reports · 2025Article
- Review
- Skin Care Practices in Indian Newborns and Infants: Current Scenario.Pediatric health, medicine and therapeutics · 2025Review
- Neonatal Sepsis: Aetiology, Pathophysiology, Diagnostic Advances and Management Strategies.Clinical medicine insights. Pediatrics · 2024Review
- From intra- to extra-uterine: early phase design of a transfer to extra-uterine life support through medical simulation.Frontiers in medical technology · 2024Article
- Effectiveness of ambulatory non-invasive fetal electrocardiography: impact of maternal and fetal characteristics.Acta obstetricia et gynecologica Scandinavica · 2023Observational
- Antimicrobial Peptides in Early-Life Host Defense, Perinatal Infections, and Necrotizing Enterocolitis-An Update.Journal of clinical medicine · 2022Review
- Distribution of Vernix Caseosa and Associated Factors Among Newborns Delivered at Adama Comprehensive Specialized Hospital Medical College, Ethiopia, in 2022: Cross-Sectional Study.Clinical, cosmetic and investigational dermatology · 2022Article
- Delivery Route and the Outcome of Newborn Hearing Screening of Full-Term Neonates Born in a Public Maternal-Infant Hospital in the South of Brazil.International archives of otorhinolaryngology · 2021Article
- DERMATOSES IN THE EARLY NEONATAL PERIOD: THEIR ASSOCIATION WITH NEONATAL, OBSTETRIC AND DEMOGRAPHIC VARIABLES.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2019Article
- β-Defensins: Farming the Microbiome for Homeostasis and Health.Frontiers in immunology · 2018Review
- Cholesteryl esters of ω-(Journal of lipid research · 2017Article
- Article
- Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders.Evolution, medicine, and public health · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vernix caseosa is a white, creamy, naturally occurring biofilm covering the skin of the fetus during the last trimester of pregnancy. Vernix coating on the neonatal skin protects the newborn skin and facilitates extra-uterine adaptation of skin in the first postnatal week if not washed away after birth. It consists of water-containing corneocytes embedded in a lipid matrix. The strategic location of the vernix on the fetal skin surface suggests participation in multiple overlapping functions required at birth, such as barrier to water loss, temperature regulation, and innate immunity. Vernix seems to perform various integral roles during transition of the fetus from intra-uterine to extra-uterine life. It has also found various interesting diagnostic and prognostic implications in this arena. Thus, it continues to be an intriguing topic of interest among the medical fraternity to understand its detailed biology and function in the fetus and also to put its naturally endowed characteristics to use in the adult population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.