ReviewCurrent opinion in genetics & development2009
The structure-function link of compensated chromatin in Drosophila.
Review in Current opinion in genetics & development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed.
- Proximity ligation assays of protein and RNA interactions in the male-specific lethal complex on Drosophila melanogaster polytene chromosomes.Chromosoma · 2015Article
- Non-coding roX RNAs prevent the binding of the MSL-complex to heterochromatic regions.PLoS genetics · 2014Article
- The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.PLoS genetics · 2014Article
- A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.The Journal of biological chemistry · 2014Article
- Targeting of Painting of fourth to roX1 and roX2 proximal sites suggests evolutionary links between dosage compensation and the regulation of the fourth chromosome in Drosophila melanogaster.G3 (Bethesda, Md.) · 2013Article
- Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression.Genome integrity · 2013Article
- Different chromatin interfaces of the Drosophila dosage compensation complex revealed by high-shear ChIP-seq.Genome research · 2013Article
- Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins.PloS one · 2013Article
- Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription.Nature reviews. Genetics · 2012Review
- Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context.PLoS genetics · 2012Article
- Epigenetic virtues of chromodomains.Critical reviews in biochemistry and molecular biology · 2011Review
- Cooperative and antagonistic contributions of two heterochromatin proteins to transcriptional regulation of the Drosophila sex determination decision.PLoS genetics · 2011Article
- Introduction--Epiphanies in epigenetics.Progress in molecular biology and translational science · 2011Article
- The transformer gene of Ceratitis capitata: a paradigm for a conserved epigenetic master regulator of sex determination in insects.Genetica · 2011Article
- Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter.PloS one · 2011Article
- Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono- or dimethyllysine 20 on histone H4.The Journal of biological chemistry · 2010Article
- Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila.BMC molecular biology · 2010Article
- Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain.Nature structural & molecular biology · 2010Article
- Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
All the aspects of transcription are controlled by complexes that modify or remodel chromatin at the level of individual genes, gene clusters, or whole chromosomes. The MSL complex that is responsible for dosage compensation in Drosophila is an example of complexes that operate at the whole-chromosome level on the transcription of individual genes. Recent experiments using traditional genetic analysis, molecular cytology, chromatin immunoprecipitation, or microarray technology have characterized the function of the two known enzymatic components of the MSL core complex and have identified the sequence characteristics that allow spreading of the complex along the X chromosome and a specific histone modification of active X-linked genes to which it is attracted. Further progress in understanding the function of this complex will benefit from biophysical approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.