Evidence map›Paper›PMID 19880286›Full record

ArticleJournal of clinical epidemiology2010

A correspondence analysis revealed frailty deficits aggregate and are multidimensional.

Nadia Sourial, Christina Wolfson, Howard Bergman, Bin Zhu, Sathya Karunananthan, Jacqueline Quail, John Fletcher, Deborah Weiss, Karen Bandeen-Roche, François Béland

Abstract read
In one paragraph

Article in Journal of clinical epidemiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Frailty and cognitive impairment in Parkinson's disease: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
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  6. Principles and Issues for Physical Frailty Measurement and Its Clinical Application.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nadia SourialSolidage Research Group, Centre for Clinical Epidemiology and Community Studies, Jewish General Hospital, Quebec, Canada.
Christina Wolfson
Howard Bergman
Bin Zhu
Sathya Karunananthan
Jacqueline Quail
John Fletcher
Deborah Weiss
Karen Bandeen-Roche
François Béland

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
CIHR 68739CIHR 82945CIHR 82945-1NIA NIH HHS P30 AG021334NIA NIH HHS P50AG-021334-01
6 · The paper itself

Abstract

objectiveTo examine the relationships among seven frailty domains: nutrition, physical activity, mobility, strength, energy, cognition, and mood, using data from three studies. STUDY DESIGN AND

settingData from three studies were separately analyzed using multiple correspondence analysis (MCA). The graphical output of MCA was used to assess (1) if the presence of deficits in the frailty domains separate from the absence of deficits on the graph, (2) the dimensionality of the domains, (3) the clustering of domains within each dimension, and (4) their relationship with age, sex, and disability. Results were compared across the studies.

resultsIn two studies, presence of deficits for all domains separated from absence of deficits. In the third study, there was separation in all domains except cognition. Three main dimensions were retained in each study; however, assigned dimensionality of domains differed. The clustering of mobility with energy and/or strength was consistent across studies. Deficits were associated with older age, female sex, and disability.

conclusionOur results suggest that frailty is a multidimensional concept for which the relationships among domains differ according to the population characteristics. These domains, with the possible exception of cognition, appear to aggregate together and share a common underlying construct.

Indexed as

AffectAgedAged, 80 and overCluster AnalysisCognitionDisability EvaluationFemaleFrail ElderlyGeriatric AssessmentHealth StatusHumansMaleMotor ActivityMuscle StrengthNutrition Assessment

Identifiers

PMID19880286
PMCPMC3718711

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.