ArticleFertility and sterility2010
Gene expression during successful implantation in a natural cycle.
Article in Fertility and sterility, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 20 citations in OpenAlex.
- Endometrial Receptivity Analysis (ERA): data versus opinions.Human reproduction open · 2021Article
- 15 years of transcriptomic analysis on endometrial receptivity: what have we learnt?Fertility research and practice · 2019Review
- Gene profiling the window of implantation: Microarray analyses from human and rodent models.Journal of reproductive health and medicine · 2016Article
- Human Endometrial Transcriptomics: Implications for Embryonic Implantation.Cold Spring Harbor perspectives in medicine · 2015Review
- Article
- Progesterone/Estradiol Ratio as a Predictor in the ART Cycles with Premature Progesterone Elevation on the Day of hCG Trigger.Journal of reproduction & infertilityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo determine the human endometrial transcriptome during embryonic implantation.
designCase report.
settingTertiary fertility center. PATIENT(S): A 24-year-old woman who inadvertently became pregnant during an endometrial biopsy procedure. INTERVENTION(S): An endometrial biopsy was performed with a Pipelle device during the midluteal phase (days 19-21) of the cycle; blood samples for hormonal assessments were collected and a transvaginal ultrasound was performed. MAIN OUTCOME MEASURE(S): Gene expression analysis of the endometrium during the window of implantation (during the implantation of an embryo) in a natural cycle. Localization of selected genes in endometrial tissue with immunohistochemistry. RESULT(S): A total of 394 probe sets were differentially expressed in the pregnant sample when compared with the midsecretory phase nonpregnant endometrial samples. Different gene networks were involved, and selected genes from these signaling pathways were confirmed at the protein level. CONCLUSION(S): Endometrial gene expression of a pregnant patient in a natural cycle is significantly different from nonpregnant patients during the midsecretory phase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.