Evidence map›Paper›PMID 19879831›Full record

ArticleCell2009

Tetherin is as tetherin does.

Jason Hammonds, Paul Spearman

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Smart self-assembled hybrid hydrogel biomaterials.Angewandte Chemie (International ed. in English) · 2012
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jason HammondsEmory University and Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
Paul Spearman
Emory University · US

Funding

Role of VPU in Retroviral Particle AssemblyR01AI058828 · NIAID · VANDERBILT UNIVERSITY · PI SPEARMAN, PAUL W. · 2004 to 2015
$3.6M
NIAID NIH HHS R01 AI058828
6 · The paper itself

Abstract

Tetherin is a cellular restriction factor that inhibits the release of HIV and other enveloped viruses from host cells. A paper from Perez-Caballero et al. (2009) in this issue of Cell clarifies how this factor works. The authors show that the aptly named tetherin directly tethers viral particles to the plasma membrane.

Indexed as

AnimalsAntigens, CDBone Marrow Stromal Antigen 2Cell MembraneGPI-Linked ProteinsHIV-1HumansMembrane GlycoproteinsVirionAntigens, CDBone Marrow Stromal Antigen 2BST2 protein, humanGPI-Linked ProteinsMembrane Glycoproteins

Identifiers

PMID19879831
OpenAlexW2116403661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.