ReviewCurrent opinion in genetics & development2009
From elements to modules: regulatory evolution in Ascomycota fungi.
Review in Current opinion in genetics & development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 14 citations in OpenAlex.
- Mitochondrial retrograde control of transcription evolves with respiratory stress, metabolic adaptation, and virulence in budding yeasts.Molecular biology and evolution · 2026Article
- Article
- Polyphasic Characterization of the Biocontrol Potential of a Novel Strain ofJournal of fungi (Basel, Switzerland) · 2024Article
- Variations in Rhizospheric and Endophytic Root Fungal Communities of Scrophularia ningpoensis in Different Producing Areas.Current microbiology · 2023Article
- Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network.EMBO reports · 2023Article
- Species-specific effects of the introduction of Aspergillus nidulans gfdB in osmophilic aspergilli.Applied microbiology and biotechnology · 2023Article
- Evolution of gene regulatory network of CPlant communications · 2023Article
- The transcriptional response to oxidative stress is independent of stress-granule formation.Molecular biology of the cell · 2022Article
- Identification of Taxonomically Restricted Transcripts from Illumina RNA Sequencing Data.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Article
- A network-based comparative framework to study conservation and divergence of proteomes in plant phylogenies.Nucleic acids research · 2021Article
- Article
- Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi.PLoS genetics · 2017Article
- Inference and Evolutionary Analysis of Genome-Scale Regulatory Networks in Large Phylogenies.Cell systems · 2017Article
- Recurrent rewiring and emergence of RNA regulatory networks.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
- Reconstruction and Analysis of the Evolution of Modular Transcriptional Regulatory Programs Using Arboretum.Methods in molecular biology (Clifton, N.J.) · 2016Article
- Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets.PLoS biology · 2015Article
- The transcription factors Tec1 and Ste12 interact with coregulators Msa1 and Msa2 to activate adhesion and multicellular development.Molecular and cellular biology · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Regulatory divergence is likely a major driving force in evolution. Comparative transcriptomics provides a new glimpse into the evolution of gene regulation. Ascomycota fungi are uniquely suited among eukaryotes for studies of regulatory evolution, because of broad phylogenetic scope, many sequenced genomes, and facility of genomic analysis. Here we review the substantial divergence in gene expression in Ascomycota and how this is reconciled with the modular organization of transcriptional networks. We show that flexibility and redundancy in both cis-regulation and trans-regulation can lead to changes from altered expression of single genes to wholesale rewiring of regulatory modules. Redundancy thus emerges as a major driving force facilitating expression divergence while preserving the coherent functional organization of a transcriptional response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.