ArticleCancer cell2009
It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma.
Article in Cancer cell, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma.Cancer letters · 2020Article
- Article
- Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Molecular mechanism of pancreatic cancer--understanding proliferation, invasion, and metastasis.Langenbeck's archives of surgery · 2010Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Despite significant efforts, the cellular compartment that gives rise to pancreatic ductal adenocarcinoma (PDAC), one of the most lethal human cancers, remains obscure. In this issue of Cancer Cell, Gidekel Friedlander and colleagues demonstrate that under conditions of tissue damage, mutant Kras can drive previously unsuspected insulin-positive endocrine cells into PDA.
Indexed as
Identifiers
19878864What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.