ReviewDrugs2009
Clinical aspects of invasive candidiasis in paediatric patients.
Review in Drugs, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Antifungal agents in current pediatric practice.Current infectious disease reports · 2013Article
- Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes.Eukaryotic cell · 2013Article
- High Levels of beta-D-glucan in immunocompromised children with proven invasive fungal disease.Clinical and vaccine immunology : CVI · 2010Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida infections in paediatric patients are an important issue. They are associated with significant mortality, particularly in newborns and those with congenital immunodeficiencies. At present, there is limited knowledge regarding factors associated with an increased risk of developing invasive candidiasis in newborns and those with congenital immunodeficiencies, although there have been a number of studies conducted to characterize these risk factors. These studies have suggested that, in neonates, the most important of these factors is colonization, whereas in paediatric patients with congenital immunodeficiencies, risk factors may differ according to the specific deficiency present. Regarding treatment of invasive candidiasis in paediatric patients, fluconazole is considered an appropriate choice, although the method for determining treatment strategies for each patient should be the same as that used for such decisions in adult patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.