ArticleJournal of the American Society of Nephrology : JASN2010
Transplant nephrectomy improves survival following a failed renal allograft.
Article in Journal of the American Society of Nephrology : JASN, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.
- The Failing Kidney Transplant Allograft. Transplant Nephrectomy: Current State-of-the-Art.Current urology reports · 2020Pooled it
- Trial
- Repeat Transplantation Rate of Patients Receiving Dialysis After Allograft Nephrectomy.Kidney medicine · 2026Article
- Losing Much More Than a Transplant: A Qualitative Study of Kidney Transplant Recipients' Experiences of Graft Failure.Kidney international reports · 2024Article
- Conservative Kidney Management in Kidney Transplant Populations.Seminars in nephrology · 2023Review
- Continuation of immunosuppression vs. immunosuppression weaning in potential repeat kidney transplant candidates: a care management perspective.Frontiers in nephrology · 2023Review
- Allograft nephrectomy vs. no nephrectomy for failed renal transplants.Frontiers in nephrology · 2023Review
- Challenges in the Management of the Patient with a Failing Kidney Graft: A Narrative Review.Journal of clinical medicine · 2022Review
- Effect of Nephrectomy After Allograft Failure on Inflammation, Erythropoiesis, Donor-Specific Antibodies, and Outcome of Re-Transplantation.Annals of transplantation · 2022Article
- Pearls and Pitfalls in Pediatric Kidney Transplantation After 5 Decades.Frontiers in pediatrics · 2022Article
- Embolization of the renal artery before graft nephrectomy: a comparing study to evaluate the possible benefits.Updates in surgery · 2021Article
- Management of patients with a failed kidney transplant: what should we do?Clinical kidney journal · 2021Review
- Histopathological examination of removed kidney allografts: Is it useful? A retrospective cohort study.Transplant international : official journal of the European Society for Organ Transplantation · 2020Article
- Transplant nephrectomy with peritoneal window: Georgetown University experience.Turkish journal of surgery · 2019Article
- Management of chronic renal allograft dysfunction and when to re-transplant.Pediatric nephrology (Berlin, Germany) · 2019Review
- Transplant nephrectomy after graft failure: is it so risky? Impact on morbidity, mortality and alloimmunization.International urology and nephrology · 2018Article
- Graft nephrectomy in children.Pediatric nephrology (Berlin, Germany) · 2018Review
- Re-Examining Risk of Repeated HLA Mismatch in Kidney Transplantation.Journal of the American Society of Nephrology : JASN · 2016Article
- Role of allograft nephrectomy following kidney graft failure: preliminary experience with pre-operative angiographic kidney embolization.Journal of nephrology · 2015Article
- Management of patients with a failed kidney transplant: Dialysis reinitiation, immunosuppression weaning, and transplantectomy.World journal of nephrology · 2015Review
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
There is a growing number of patients returning to dialysis after a failed kidney transplant, and there is increasing evidence of higher mortality among this population. Whether removal of the failed renal allograft affects survival while receiving long-term dialysis is not well understood. We identified all adults who received a kidney transplant and returned to long-term dialysis after renal allograft failure between January 1994 and December 2004 from the US Renal Data System. Among 10,951 transplant recipients who returned to long-term dialysis, 3451 (31.5%) received an allograft nephrectomy during follow-up. Overall, 34.6% of these patients died during follow-up. Receiving an allograft nephrectomy associated with a 32% lower adjusted relative risk for all-cause death (adjusted hazard ratio 0.68; 95% confidence interval 0.63 to 0.74) after adjustment for sociodemographic characteristics, comorbidity burden, donor characteristics, interim clinical conditions associated with receiving allograft nephrectomy, and propensity to receive an allograft nephrectomy. In conclusion, within a large, nationally representative sample of high-risk patients returning to long-term dialysis after failed kidney transplant, receipt of allograft nephrectomy independently associated with improved survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.