ArticleVector borne and zoonotic diseases (Larchmont, N.Y.)2010
DNA vaccination of American robins (Turdus migratorius) against West Nile virus.
Article in Vector borne and zoonotic diseases (Larchmont, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Review
- Ecological drivers of arboviral disease risk: Vector-host interfaces in a Mediterranean wetland of Northeastern Spain.PLoS neglected tropical diseases · 2025Article
- Reservoir hosts experiencing food stress alter transmission dynamics for a zoonotic pathogen.Proceedings. Biological sciences · 2021Article
- The Key Role of Nucleic Acid Vaccines for One Health.Viruses · 2021Review
- Current Progress of Avian Vaccines Against West Nile Virus.Vaccines · 2019Review
- Review
- Assessing Interventions to Manage West Nile Virus Using Multi-Criteria Decision Analysis with Risk Scenarios.PloS one · 2016Article
- Evaluation of Cross-Protection of a Lineage 1 West Nile Virus Inactivated Vaccine against Natural Infections from a Virulent Lineage 2 Strain in Horses, under Field Conditions.Clinical and vaccine immunology : CVI · 2015Article
- DNA vaccines encoding the envelope protein of West Nile virus lineages 1 or 2 administered intramuscularly, via electroporation and with recombinant virus protein induce partial protection in large falcons (Falco spp.).Veterinary research · 2015Article
- Improvement of DNA vaccination by adjuvants and sophisticated delivery devices: vaccine-platforms for the battle against infectious diseases.Clinical and experimental vaccine research · 2015Review
- Limited efficacy of West Nile virus vaccines in large falcons (Falco spp.).Veterinary research · 2014Article
- Article
- The dichotomy of pathogens and allergens in vaccination approaches.Frontiers in microbiology · 2014Review
- Flaviviruses in Europe: complex circulation patterns and their consequences for the diagnosis and control of West Nile disease.International journal of environmental research and public health · 2013Review
- Article
- Drivers, dynamics, and control of emerging vector-borne zoonotic diseases.Lancet (London, England) · 2012Review
- Disease and the dynamics of extinction.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2012Article
- The ecology of emerging infectious diseases in migratory birds: an assessment of the role of climate change and priorities for future research.EcoHealth · 2012Review
- Characterization of Rabensburg virus, a flavivirus closely related to West Nile virus of the Japanese encephalitis antigenic group.PloS one · 2012Article
- Efficacy of three vaccines in protecting Western Scrub-Jays (Aphelocoma californica) from experimental infection with West Nile virus: implications for vaccination of Island Scrub-Jays (Aphelocoma insularis).Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
West Nile virus (WNV) has caused at least 1150 cases of encephalitis, 100 deaths, and an estimated 30,000-80,000 illnesses in 6 of the last 7 years. Recent evidence from several regions has implicated American robins (Turdus migratorius) as an important host for feeding by Culex mosquitoes, and, when integrated with their host competence for WNV, demonstrates that they are a key WNV amplification host. We evaluated the efficacy of a DNA plasmid vaccine at reducing the viremia and infectiousness of hatch-year American robins. We found that a single dose of vaccine injected intramuscularly resulted in more than a 400-fold (10(2.6)) decrease in average viremia. Although sample sizes were small, these results suggest that vaccinated robins exhibit viremias that are likely to be mostly noninfectious to biting Culex mosquitoes. More broadly, if an orally effective formulation of this vaccine could be developed, new control strategies based on wildlife vaccination may be possible.
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