Evidence map›Paper›PMID 19865527›Full record

Trial reportInternational journal of molecular sciences2009

Sage tea drinking improves lipid profile and antioxidant defences in humans.

Carla M Sá, Alice A Ramos, Marisa F Azevedo, Cristovao F Lima, Manuel Fernandes-Ferreira, Cristina Pereira-Wilson

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of molecular sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 89 citations in OpenAlex.

  1. Trial
  2. Review
  3. Exploring the Therapeutic Potential ofJournal of clinical medicine · 2025
    Review
  4. An Ethnopharmacological Survey on Medicinally Important Plants of Genus Salvia.Combinatorial chemistry & high throughput screening · 2025
    Review
  5. Article
  6. Current pharmaceutical biotechnology · 2024
    Article
  7. Article
  8. Article
  9. Immunomodulatory Effects of Plant Extracts fromPlants (Basel, Switzerland) · 2022
    Article
  10. Review
  11. Review
  12. Bioactive Components ofMolecules (Basel, Switzerland) · 2021
    Review
  13. Bioactive Profile of VariousPlants (Basel, Switzerland) · 2019
    Review
  14. Pharmacological properties ofJournal of traditional and complementary medicine · 2017
    Article
  15. Article
  16. Effects on Liver Lipid Metabolism of the Naturally Occurring Dietary Flavone Luteolin-7-glucoside.Evidence-based complementary and alternative medicine : eCAM · 2015
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carla M SáCBMA-Centre of Molecular and Environmental Biology/Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Alice A RamosCBMA-Centre of Molecular and Environmental Biology/Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Marisa F AzevedoCBMA-Centre of Molecular and Environmental Biology/Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Cristovao F LimaCITAB-Centre for the Research and Technology of Agro-Environment and Biological Sciences/Department of Biology, School of Sciences, University of Minho, 4710-057 Braga, Portugal.
Manuel Fernandes-FerreiraCITAB-Centre for the Research and Technology of Agro-Environment and Biological Sciences/Department of Biology, School of Sciences, University of Minho, 4710-057 Braga, Portugal.
Cristina Pereira-WilsonCBMA-Centre of Molecular and Environmental Biology/Department of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
University of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salvia officinalis (common sage) is a plant with antidiabetic properties. A pilot trial (non-randomized crossover trial) with six healthy female volunteers (aged 40-50) was designed to evaluate the beneficial properties of sage tea consumption on blood glucose regulation, lipid profile and transaminase activity in humans. Effects of sage consumption on erythrocytes' SOD and CAT activities and on Hsp70 expression in lymphocytes were also evaluated. Four weeks sage tea treatment had no effects on plasma glucose. An improvement in lipid profile was observed with lower plasma LDL cholesterol and total cholesterol levels as well as higher plasma HDL cholesterol levels during and two weeks after treatment. Sage tea also increased lymphocyte Hsp70 expression and erythrocyte SOD and CAT activities. No hepatotoxic effects or other adverse effects were observed.

Indexed as

BeveragesAdministration, OralAdultAlanine TransaminaseAntioxidantsAspartate AminotransferasesBlood GlucoseBlood PressureCatalaseCholesterol, LDLCross-Over StudiesDiabetes Mellitus, Type 2FemaleHeart RateHep G2 CellsHSP70 Heat-Shock ProteinsAlanine TransaminaseAntioxidantsAspartate AminotransferasesBlood GlucoseCatalaseCholesterol, LDLHSP70 Heat-Shock ProteinsHypoglycemic AgentsLipidsPlant ExtractsSuperoxide Dismutaseantioxidant defenceshuman triallipid profileSalvia officinalis L.type 2 diabetes mellitus

Identifiers

PMID19865527
PMCPMC2769154
OpenAlexW2153402240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.