Evidence map›Paper›PMID 19864294›Full record

Trial reportEuropean journal of endocrinology2010

Enhanced insulin sensitivity after acute exercise is not associated with changes in high-molecular weight adiponectin concentration in plasma.

Faidon Magkos, B Selma Mohammed, Bettina Mittendorfer

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in European journal of endocrinology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. The effect of acute exercise on undercarboxylated osteocalcin in obese men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
    Trial
  2. Article
  3. Review
  4. Plasma Apelin Unchanged With Acute Exercise Insulin Sensitization.Journal of sports science & medicine · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Faidon MagkosDepartment of Nutrition and Dietetics, Harokopio University, Athens, Greece. faimag@hua.gr
B Selma Mohammed
Bettina Mittendorfer
Harokopio University of Athens · GR

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
YOGA LIFESTYLE INTERVENTION REDUCES BLOOD PRESSURE IN HIV-INFECTED ADULTSP41RR000954 · NCRR · WASHINGTON UNIVERSITY · PI GROSS, MICHAEL L · 1985 to 2011
$16.0M
Sleep and Metabolism in Obesity: Impact of GenderP50HD057796 · NICHD · UNIVERSITY OF CHICAGO · PI EHRMANN, DAVID A · 2007 to 2011
$5.9M
Effects of sex and adiposity on muscle protein synthesisR01AR049869 · NIAMS · WASHINGTON UNIVERSITY · PI MITTENDORFER, BETTINA · 2004 to 2008
$1.6M
NCRR NIH HHS P41 RR000954NCRR NIH HHS RR 00954NCRR NIH HHS UL1 RR024992NIAMS NIH HHS AR 49869NIAMS NIH HHS R01 AR049869NICHD NIH HHS HD 057796NICHD NIH HHS P50 HD057796NIDDK NIH HHS DK 56341NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe effect of exercise on the plasma concentration of high-molecular weight (HMW) adiponectin (i.e. the biologically active form of circulating adiponectin) and the possible role of HMW adiponectin in mediating the exercise-induced enhancement of insulin action are not known. The aim of this study was to evaluate the relationship between the post-exercise increase in insulin sensitivity and plasma HMW adiponectin concentration. DESIGN AND

methodsWe measured total and HMW adiponectin concentrations in plasma using an ELISA kit, and insulin sensitivity using the updated homeostasis model assessment of insulin sensitivity (HOMA2-IS) score in the basal, overnight fasted state, once approximately 12 h after a single bout of moderate-intensity endurance exercise and once after an equivalent period of rest, in 27 healthy men and women (age: 29+/-1 years and body mass index: 24.7+/-0.8 kg/m(2)).

resultsThe HOMA2-IS score was 18+/-7% greater after exercise than after rest (229+/-20 and 196+/-17 respectively; P=0.006), whereas the concentrations of total adiponectin (7.8+/-0.5 and 7.7+/-0.5 mg/l respectively; P=0.597) and HMW adiponectin (3.0+/-0.3 and 3.0+/-0.3 mg/l respectively; P=0.625) were not different. The exercise-induced change in HOMA2-IS score was not related to changes in total and HMW adiponectin concentrations (P>0.3).

conclusionsChanges in HMW adiponectin concentration are not involved in the acute exercise-induced enhancement of insulin action.

Indexed as

AdiponectinAdultBlood GlucoseExerciseFemaleHomeostasisHumansInsulinInsulin ResistanceMaleTime FactorsAdiponectinBlood GlucoseInsulin

Identifiers

PMID19864294
PMCPMC3557821
OpenAlexW2135434554

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.