ArticleProceedings. Biological sciences2010
Culture-gene coevolution of individualism-collectivism and the serotonin transporter gene.
Article in Proceedings. Biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 2 of them syntheses that pooled it.
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123 citing papers in PubMed, 2 syntheses or guidelines pooled it.
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- The Relative Role of Family Affluence and Social Support on Depression and Self-Esteem among Adolescents in Nigeria: a Cross-Sectional Study.Acta medica academica · 2023Article
- Examining the Relationships between the Incidence of Infectious Diseases and Mood Disorders: An Analysis of Data from the Global Burden of Disease Studies, 1990-2019.Diseases (Basel, Switzerland) · 2023Article
- Genetic predictors of cultural values variation between societies.Scientific reports · 2023Article
- Of Germs and Culture; Parasite Stress as the Origin of Individualism-Collectivism.Evolutionary psychological science · 2023Article
- Developing and validating a Japanese version of the Plymouth Sensory Imagery Questionnaire.Frontiers in psychology · 2023Article
- Cultural collectivism, intimate partner violence, and women's mental health: An analysis of data from 151 countries.Frontiers in sociology · 2023Article
63 more citing papers are in PubMed but not listed here.
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Abstract
Culture-gene coevolutionary theory posits that cultural values have evolved, are adaptive and influence the social and physical environments under which genetic selection operates. Here, we examined the association between cultural values of individualism-collectivism and allelic frequency of the serotonin transporter functional polymorphism (5-HTTLPR) as well as the role this culture-gene association may play in explaining global variability in prevalence of pathogens and affective disorders. We found evidence that collectivistic cultures were significantly more likely to comprise individuals carrying the short (S) allele of the 5-HTTLPR across 29 nations. Results further show that historical pathogen prevalence predicts cultural variability in individualism-collectivism owing to genetic selection of the S allele. Additionally, cultural values and frequency of S allele carriers negatively predict global prevalence of anxiety and mood disorder. Finally, mediation analyses further indicate that increased frequency of S allele carriers predicted decreased anxiety and mood disorder prevalence owing to increased collectivistic cultural values. Taken together, our findings suggest culture-gene coevolution between allelic frequency of 5-HTTLPR and cultural values of individualism-collectivism and support the notion that cultural values buffer genetically susceptible populations from increased prevalence of affective disorders. Implications of the current findings for understanding culture-gene coevolution of human brain and behaviour as well as how this coevolutionary process may contribute to global variation in pathogen prevalence and epidemiology of affective disorders, such as anxiety and depression, are discussed.
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