ReviewJournal of cellular and molecular medicine
Sensing, physiological effects and molecular response to elevated CO2 levels in eukaryotes.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 53 citations in OpenAlex.
- Machine learning-derived serum carbon dioxide trajectories in predicting prognosis of patients with acute aortic dissection.Medical gas research · 2027Article
- Sensing molecular carbon dioxide: a translational focus for respiratory disease.Physiological reviews · 2025Review
- Qingre huazhuo tang regulates IgA nephropathy through immune checkpoints and ferroptosis.Journal of traditional and complementary medicine · 2025Article
- Elevated carbon dioxide enhances the growth and reduces the antifungal susceptibility ofMicrobiology spectrum · 2025Article
- Systolic versus diastolic differences in cerebrovascular reactivity to hypercapnic and hypocapnic challenges.European journal of applied physiology · 2025Article
- The Impact of Microelectrode Pattern on the Sensitivity of Tracing Environmental COBiosensors · 2023Article
- Imaginal disk growth factors are Drosophila chitinase-like proteins with roles in morphogenesis and CO2 response.Genetics · 2023Article
- Responses of the MushroomJournal of fungi (Basel, Switzerland) · 2022Article
- Drosophila melanogaster Stress Odorant (dSO) Displays the Characteristics of an Interspecific Alarm Cue.Journal of chemical ecology · 2021Article
- A methodology for carbamate post-translational modification discovery and its application inInterface focus · 2021Article
- Altered functional properties of the codling moth Orco mutagenized in the intracellular loop-3.Scientific reports · 2021Article
- Comparative Transcriptomics ofInternational journal of molecular sciences · 2019Article
- Fossorial Damaraland mole rats do not exhibit a blunted hypercapnic ventilatory response.Biology letters · 2019Article
- Behavioural responses to environmental hypercapnia in two eusocial species of African mole rats.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018Article
- COCurrent genetics · 2017Review
- Article
- Gas Exchange Disturbances Regulate Alveolar Fluid Clearance during Acute Lung Injury.Frontiers in immunology · 2017Review
- Intermittent hypoxia in childhood: the harmful consequences versus potential benefits of therapeutic uses.Frontiers in pediatrics · 2015Review
- The response to high CO2 levels requires the neuropeptide secretion component HID-1 to promote pumping inhibition.PLoS genetics · 2014Article
- A chemoreceptor that detects molecular carbon dioxide.The Journal of biological chemistry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Carbon dioxide (CO(2)) is an important gaseous molecule that maintains biosphere homeostasis and is an important cellular signalling molecule in all organisms. The transport of CO(2) through membranes has fundamental roles in most basic aspects of life in both plants and animals. There is a growing interest in understanding how CO(2) is transported into cells, how it is sensed by neurons and other cell types and in understanding the physiological and molecular consequences of elevated CO(2) levels (hypercapnia) at the cell and organism levels. Human pulmonary diseases and model organisms such as fungi, C. elegans, Drosophila and mice have been proven to be important in understanding of the mechanisms of CO(2) sensing and response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.