ArticleEuropean radiology2010
Correlation of regional distribution and morphological pattern of calcification at CT coronary artery calcium scoring with non-calcified plaque formation and stenosis.
Article in European radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- The role of coronary artery calcium scoring in the prediction of coronary artery disease based on non-contrast non-cardiac chest CT scans in airline pilots.Frontiers in cardiovascular medicine · 2025Article
- [Assessment of Coronary Stenosis Using Coronary CT Angiography in Patients with High Calcium Scores: Current Limitations and Future Perspectives].Journal of the Korean Society of Radiology · 2024Review
- Improved bias and reproducibility of coronary artery calcification features using deconvolution.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Imaging Cardiovascular Calcification.Journal of the American Heart Association · 2018Review
- The Coronary Artery Running Pattern is One of the Causes of Individual Differences in the Progression of Coronary Atherosclerosis in WHHLMI Rabbits, an Animal Model for Coronary Atherosclerosis.Journal of atherosclerosis and thrombosis · 2018Article
- Relation of Diastolic Blood Pressure and Coronary Artery Calcium to Coronary Events and Outcomes (From the Multi-Ethnic Study of Atherosclerosis).The American journal of cardiology · 2017Article
- Correlation and predictive value of aortic root calcification markers with coronary artery calcification and obstructive coronary artery disease.La Radiologia medica · 2017Article
- Progression of coronary artery calcification at the crossroads: sign of progression or stabilization of coronary atherosclerosis?Cardiovascular diagnosis and therapy · 2016Review
- The challenge of coronary calcium on coronary computed tomographic angiography (CCTA) scans: effect on interpretation and possible solutions.The international journal of cardiovascular imaging · 2015Review
- Integrated cardiac magnetic resonance imaging with coronary magnetic resonance angiography, stress-perfusion, and delayed-enhancement imaging for the detection of occult coronary artery disease in asymptomatic individuals.The international journal of cardiovascular imaging · 2015Article
- Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability.Current opinion in lipidology · 2014Review
- Comparison of position, morphology and calcification of Coronary Plaque with 320-row dynamic volume CT (DVCT) and coronary angiography (CAG).Pakistan journal of medical sciences · 2014Article
- Value of segmental coronary calcium score on diagnosis and interventional treatment of coronary lesions by 320-slice DVCT.International journal of clinical and experimental medicine · 2014Article
- Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- The explosive growth of small voids in vulnerable cap rupture; cavitation and interfacial debonding.Journal of biomechanics · 2013Article
- A mechanistic analysis of the role of microcalcifications in atherosclerotic plaque stability: potential implications for plaque rupture.American journal of physiology. Heart and circulatory physiology · 2012Article
- Coronary artery calcium scoring, what is answered and what questions remain.Cardiovascular diagnosis and therapy · 2012Review
- Coronary artery calcium scoring and its impact on the clinical practice in the era of multidetector CT.The international journal of cardiovascular imaging · 2011Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether regional calcification patterns at CT coronary artery calcium scoring (CCS) correlate with stenosis and non-calcified plaque formation.
methodsWe studied 106 patients with quantitative catheter angiography (QCA), CCS, and coronary CT angiography (cCTA). CCS was determined globally and for each artery separately. The morphological pattern of each calcification was classified as calcified nodule, shell-like, or diffuse. cCTA studies were evaluated for non-calcified plaque. The global and regional CCS and the calcification pattern were correlated with stenosis >or=50% and non-calcified plaque.
resultsA total of 48/106 patients had stenosis >or=50% on QCA. There was weak correlation (r = 0.36) of the global CCS with stenosis. Correlation was stronger per vessel (r = 0.55-r = 0.67). Shell-like and diffuse calcifications were significantly (p = 0.0001) more frequently associated with >or=50% stenosis and non-calcified plaque (p = 0.04) than calcified nodules.
conclusionAs shown before, the global CCS does not correlate well with stenosis. However, regional calcium distribution and specific patterns of calcification are correlated with stenosis and non-calcified plaque. Thus, the specificity of CT calcium scoring for identifying individuals with obstructive disease could be improved by vessel-based rather than global quantification of calcium and by differentiating specific morphological patterns of calcification.
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