ReviewRheumatology international2011
Recurrent pneumothorax associated with pulmonary nodules after leflunomide therapy in rheumatoid arthritis: a case report and review of the literature.
Review in Rheumatology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Recurrent Secondary Spontaneous Pneumothorax Due to Rheumatoid Arthritis: A Report of a Rare Case.Cureus · 2025Article
- Pulmonary Nodules After Leflunomide Therapy in Rheumatoid Arthritis: A Case Report.Clinical case reports · 2025Article
- Treatment with biologic DMARDs may not adversely affect lung nodules in rheumatoid arthritis patients.European journal of rheumatology · 2022Article
- Outcome of solid and cavitary pulmonary nodules in rheumatoid arthritis patients-case series.Turkish journal of medical sciences · 2022Article
- Pulmonary air leak syndrome in rheumatoid arthritis patient.SAGE open medical case reports · 2022Article
- Cavitary pulmonary nodules in rheumatoid arthritis; case reports and review of the literature.European journal of rheumatology · 2018Article
- Practical Management of Respiratory Comorbidities in Patients with Rheumatoid Arthritis.Rheumatology and therapy · 2017Review
- Intra-thoracic rheumatoid arthritis: Imaging spectrum of typical findings and treatment related complications.European journal of radiology · 2015Review
- [Spontaneous pneumothorax as an evolutionary manifestation of rheumatoid arthritis: report of clinical observation and review of the literature].The Pan African medical journal · 2015Review
- Unusual causes of pneumothorax.Journal of thoracic disease · 2014Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatoid arthritis (RA) is a multisystem inflammatory disease characterized by destructive synovitis and systemic extraarticular involvement. One of the most common pulmonary manifestations of RA is rheumatoid nodule. Spontaneous pneumothorax also very rare pulmonary finding and could be associated with pulmonary nodules. Antirheumatic drugs, methotrexate, leflunomide (LEF), infliximab and etanercept, were known as risk factors for developing rheumatoid nodule. However, there was no case report of rheumatoid nodule-associated pneumothorax with the use of LEF. We report, first, herein a case of 46-year-old woman with RA who suffered recurrent spontaneous pneumothorax associated with multiple bilateral subpleural cavitary nodules during treatment with LEF. We reviewed the cases of LEF-related pulmonary nodules developed in patients with RA. Thus, we suggested that pneumothorax can be a rare respiratory fatal complication in patients with RA with pulmonary nodules and LEF can be a rare cause of these manifestations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.