SynthesisBritish journal of cancer2009
Pickled vegetables and the risk of oesophageal cancer: a meta-analysis.
Synthesis in British journal of cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Role of diet in the risks of esophageal adenocarcinoma and squamous cell carcinoma: an updated umbrella review.European journal of nutrition · 2024Pooled it
- Dried Fruit Intake and Cancer: A Systematic Review of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Modifiable factors and esophageal cancer: a systematic review of published meta-analyses.Journal of gastroenterology · 2018Pooled it
- The association between physical activity and gastroesophageal cancer: systematic review and meta-analysis.European journal of epidemiology · 2014Pooled it
- Outcomes from a prospective trial of endoscopic radiofrequency ablation of early squamous cell neoplasia of the esophagus.Gastrointestinal endoscopy · 2011Trial
- Paradigm Shift of Microbiota-gut-brain Axis During Aging: Potential Role of Probiotics to Improve Cognitive Decline.Probiotics and antimicrobial proteins · 2026Review
- Unmasking inequalities in gastrointestinal cancer outcomes among Asian American subpopulations.Scientific reports · 2026Article
- A full-cycle integrated management model for esophageal cancer in county health systems: effects on care processes, clinical outcomes, quality of life, and cost-utility.Frontiers in oncology · 2026Article
- An Assessment of Sociodemographic Factors, Attitude, Knowledge, and Practices of the Elderly's Caregivers with Respect to Elderly Food Safety.Foods (Basel, Switzerland) · 2025Article
- Functions and mechanisms of long non-coding RNA in esophageal squamous cell carcinoma (Review).Oncology letters · 2025Review
- Age differences in food safety knowledge, attitudes, and practices among consumers in Seoul.Nutrition research and practice · 2025Article
- Development and external validation of a nomogram for predicting the risk of developing esophageal cancer based on a questionnaire: a multicenter case-control study.Frontiers in oncology · 2025Article
- Epidemiological trends and projections of esophageal cancer in BRICS-plus: Based on the GBD 2021 database.Frontiers in oncology · 2025Article
- Preserved vegetable consumption and gastrointestinal tract cancers: A prospective study.Journal of global health · 2024Article
- Our extended microbiome: The human-relevant metabolites and biology of fermented foods.Cell metabolism · 2024Review
- Mortality burden and future projections of major risk factors for esophageal cancer in China from 1990 to 2019.General thoracic and cardiovascular surgery · 2024Article
- Burden of Gastrointestinal Tumors in Asian Countries, 1990-2021: An Analysis for the Global Burden of Disease Study 2021.Clinical epidemiology · 2024Article
- Disease burden of esophageal cancer attributable to low fruit intake in China and globally from 1990 to 2019.American journal of translational research · 2024Article
- Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3'3-diindolylmethane suppresses esophageal cancer tumorigenesis.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023Article
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundEcological and experimental studies have suggested a relationship between Asian pickled vegetable consumption and oesophageal squamous cell carcinoma (OSCC), but the results of epidemiological studies investigating the association have been inconsistent. We conducted a meta-analysis of observational studies of this association to evaluate the existing evidence.
methodsWe searched the PubMed, ISI-Web of Science, J-EAST, IndMed, Vip Chinese Periodical, and China National Knowledge Infrastructure databases for all studies published in English or Chinese languages. Pooled results for all studies combined and for several study subgroups were computed.
resultsA total of 34 studies were included in this analysis. The overall random effects odds ratio (OR) and 95% confidence interval (CI) for pickled vegetable consumption was 2.08 (1.66-2.60), but the results were heterogeneous across studies. After excluding the three most influential studies, the respective numbers were 2.32 (1.92-2.81). Similar to the overall association, the majority of subgroup analyses showed a statistically significant association between consuming pickled vegetables and OSCC risk. There were only three prospective studies.
conclusionOur results suggest a potential two-fold increased risk of oesophageal cancer associated with the intake of pickled vegetables. However, because the majority of data was from retrospective studies and there was a high heterogeneity in the results, further well-designed prospective studies are warranted.
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