ArticleEmerging infectious diseases2009
Mycobacterium tuberculosis genotype and case notification rates, rural Vietnam, 2003-2006.
Article in Emerging infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 14 citations in OpenAlex.
- Genetic Diversity of Drug-resistantAdvanced biomedical research · 2018Article
- Genetic Lineages of Mycobacterium tuberculosis Isolates in Isfahan, Iran.Current microbiology · 2017Article
- Mycobacterium tuberculosis lineages and anti-tuberculosis drug resistance in reference hospitals across Viet Nam.BMC microbiology · 2016Article
- Molecular epidemiology of tuberculosis in Cambodian children.Epidemiology and infection · 2015Article
- Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.Emerging infectious diseases · 2012Article
- First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal.PloS one · 2012Article
- Contact investigation in households of patients with tuberculosis in Hanoi, Vietnam: a prospective cohort study.PloS one · 2012Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
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Abstract
Tuberculosis case notification rates (CNRs) for young adults in Vietnam are increasing. To determine whether this finding could reflect emergence of Mycobacterium tuberculosis Beijing genotype, we studied all new sputum smear-positive pulmonary tuberculosis patients registered for treatment in 3 rural districts in Vietnam during 2003-2006. Beijing strain infections were more frequent in younger patients (15-24 years of age, 53%) than in older patients (31%; p<0.001). The increase in CNRs for youngest patients was larger for disease caused by the Beijing genotype than by other genotypes, but the difference was not significant. For patients 15-24 years of age, 85% of fluctuations in CNRs between years was caused by fluctuations in Beijing genotype infections compared with 53% and 23% in the groups 25-64 and >or=65 years of age, respectively (p<0.001). These findings suggest that young adults may be responsible for introducing Beijing strains into rural Vietnam.
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