ArticleBMC genetics2009
Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans.
Article in BMC genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Genetic data and population structure of 10 DIP-STR markers across four US population groups.International journal of legal medicine · 2026Article
- Performance of a self-developed panel for biogeographic ancestry inference and dissection of the genetic background of three Tibetan groups.Hereditas · 2025Article
- Forensic DNA phenotyping: a review on SNP panels, genotyping techniques, and prediction models.Forensic sciences research · 2025Review
- Forensic biogeographical ancestry inference: recent insights and current trends.Genes & genomics · 2023Review
- Assessment of the effectiveness of the EUROFORGEN NAME and Precision ID Ancestry panel markers for ancestry investigations.Scientific reports · 2021Article
- Article
- Identification of Ancestry Informative Marker (AIM) Panels to Assess Hybridisation between Feral and Domestic Sheep.Animals : an open access journal from MDPI · 2020Article
- Ancestry-informative marker (AIM) SNP panel for the Malay population.International journal of legal medicine · 2020Article
- An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes.Nature communications · 2016Article
- Genetic structure and differentiation analysis of a Eurasian Uyghur population by use of 27 continental ancestry-informative SNPs.International journal of legal medicine · 2016Article
- A single-tube 27-plex SNP assay for estimating individual ancestry and admixture from three continents.International journal of legal medicine · 2016Article
- Inference of biogeographical ancestry across central regions of Eurasia.International journal of legal medicine · 2016Article
- Ethnic characterization of a population of children exposed to high doses of arsenic via drinking water and a possible correlation with metabolic processes.International journal of molecular epidemiology and genetics · 2014Article
- The National DNA Data Bank of Canada: a Quebecer perspective.Frontiers in genetics · 2013Review
- First all-in-one diagnostic tool for DNA intelligence: genome-wide inference of biogeographic ancestry, appearance, relatedness, and sex with the Identitas v1 Forensic Chip.International journal of legal medicine · 2013Article
- Article
- Polymorphic NumtS trace human population relationships.Human genetics · 2012Article
- Straightforward inference of ancestry and admixture proportions through ancestry-informative insertion deletion multiplexing.PloS one · 2012Article
- Evaluation of approaches for identifying population informative markers from high density SNP chips.BMC genetics · 2011Article
- Improving human forensics through advances in genetics, genomics and molecular biology.Nature reviews. Genetics · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe identification and use of Ancestry-Sensitive Markers (ASMs), i.e. genetic polymorphisms facilitating the genetic reconstruction of geographical origins of individuals, is far from straightforward.
resultsHere we describe the ascertainment and application of five different sets of 47 single nucleotide polymorphisms (SNPs) allowing the inference of major human groups of different continental origin. For this, we first used 74 cell lines, representing human males from six different geographical areas and screened them with the Affymetrix Mapping 10K assay. In addition to using summary statistics estimating the genetic diversity among multiple groups of individuals defined by geography or language, we also used the program STRUCTURE to detect genetically distinct subgroups. Subsequently, we used a pairwise F(ST) ranking procedure among all pairs of genetic subgroups in order to identify a single best performing set of ASMs. Our initial results were independently confirmed by genotyping this set of ASMs in 22 individuals from Somalia, Afghanistan and Sudan and in 919 samples from the CEPH Human Genome Diversity Panel (HGDP-CEPH)
conclusionBy means of our pairwise population F(ST) ranking approach we identified a set of 47 SNPs that could serve as a panel of ASMs at a continental level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.