Evidence map›Paper›PMID 19859991›Full record

ReviewWorld journal of gastroenterology2009

Achalasia: a review of Western and Iranian experiences.

Javad Mikaeli, Farhad Islami, Reza Malekzadeh

Open access · hybridAbstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Optimizing achalasia diagnosis in the era of high-resolution manometry: A Pakistani perspective.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  2. Article
  3. Article
  4. Epidemiologic Study of Gastric Cancer in Iran: A Systematic Review.Clinical and experimental gastroenterology · 2020
    Review
  5. Article
  6. Is There Any Evidence for a Viral Cause in Achalasia?Middle East journal of digestive diseases · 2018
    Article
  7. Article
  8. Review
  9. High-resolution manometry is comparable to timed barium esophagogram for assessing response to pneumatic dilation in patients with achalasia.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2015
    Article
  10. Article
  11. Article
  12. Training in peroral endoscopic myotomy (POEM) for esophageal achalasia.Therapeutics and clinical risk management · 2012
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 4 countries.

Javad Mikaeli
Farhad Islami
Reza Malekzadeh
Centre International de Recherche sur le Cancer · FRKing's College London · GBTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achalasia is a primary motor disorder of the esophagus, in which esophageal emptying is impaired. Diagnosis of achalasia is based on clinical findings. The diagnosis is confirmed by radiographic, endoscopic, and manometric evaluations. Several treatments for achalasia have been introduced. We searched the PubMed Database for original articles and meta-analyses about achalasia to summarize the current knowledge regarding this disease, with particular focus on different procedures that are used for treatment of achalasia. We also report the Iranian experience of treatment of this disease, since it could be considered as a model for medium-resource countries. Myotomy, particularly laparoscopic myotomy with fundoplication, is the most effective treatment for achalasia. Compared to other treatments, however, the initial cost of myotomy is usually higher and the recovery period is longer. When performing myotomy is not indicated or not possible, graded pneumatic dilation with slow rate of balloon inflation seems to be an effective and safe initial alternative. Injection of botulinum toxin into the lower esophageal sphincter before pneumatic dilation may increase remission rates. However, this needs to be confirmed in further studies. Due to lack of adequate information regarding the role of expandable stents in the treatment of achalasia, insertion of stents does not currently seem to be a recommended treatment. In summary, laparoscopic myotomy can be considered as the procedure of choice for treatment of achalasia. Graded pneumatic dilation is an effective alternative when the performance of myotomy is not possible for any reason.

Indexed as

AdultCatheterizationEsophageal AchalasiaEsophageal DiseasesEsophagusFemaleFundoplicationGastroenterologyHumansIranMaleMiddle AgedRemission InductionRiskStentsTreatment Outcome

Identifiers

PMID19859991
PMCPMC2768877
OpenAlexW2046611938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.