Evidence map›Paper›PMID 19857388›Full record

ArticleCurrent infectious disease reports2009

HIV and the Kidney.

Leslie A Bruggeman, Charles Bark, Robert C Kalayjian

Abstract read
In one paragraph

Article in Current infectious disease reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. End-stage renal disease among HIV-infected adults in North America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
    Article
  6. Article
  7. Article
  8. Accelerated Aging in HIV Patients.Rambam Maimonides medical journal · 2012
    Article
  9. Renal leishmaniasis as unusual cause of nephrotic syndrome in an HIV patient.Journal of the American Society of Nephrology : JASN · 2012
    Article
  10. Renal issues in HIV infection.Current HIV/AIDS reports · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Leslie A BruggemanDivision of Infectious Diseases, MetroHealth Medical Center and Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44102, USA. rkalayjian@metrohealth.org
Charles Bark
Robert C Kalayjian
Case Western Reserve University · USMetroHealth · USMetroHealth Medical Center · US

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Sharon L. Hillier, JONATHAN KARN · 1994 to 2026
$50.0M
WOMEN'S HEALTH AGENDAU01AI025879 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI LEDERMAN, MICHAEL MARCEL · 1987 to 2006
$14.0M
Transcriptional regulation in chronic renal disease pathogenesisR01DK061395 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI BRUGGEMAN, LESLIE A · 2001 to 2008
$1.6M
NIAID NIH HHS P30 AI036219NIAID NIH HHS U01 AI025879NIDDK NIH HHS R01 DK061395
6 · The paper itself

Abstract

Direct effects of HIV-1 infection on the kidney combine with immune and genetic factors, comorbidities, coinfections, and medication toxicities to induce a spectrum of kidney disorders in HIV disease. The most dramatic of these, HIV-associated nephropathy (HIVAN), emerges almost exclusively in persons of African descent and is associated with rapid progression to end-stage renal disease in the absence of antiretroviral therapy (ART). ART modifies the natural history of HIVAN, but the renal benefits of ART may not be limited to HIVAN. ART is often under prescribed or incorrectly dosed in persons with kidney disease. Vigilant attention to renal function and an understanding of the complex associations involving the kidneys are necessary for optimal care of these patients.

Identifiers

PMID19857388
PMCPMC2789290
OpenAlexW1972829962

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.