ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2009
T cell dynamics and the response to HAART in a cohort of HIV-1-infected elite suppressors.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- A SpecificFrontiers in immunology · 2020Trial
- ART in HIV-Positive Persons With Low Pretreatment Viremia: Results From the START Trial.Journal of acquired immune deficiency syndromes (1999) · 2019Trial
- T Cell Homeostasis Disturbances in a Cohort of Long-Term Elite Controllers of HIV Infection.International journal of molecular sciences · 2024Article
- CCR5∆32 and SDF1 3'A: Gene Variants, Expression and Influence on Biological Markers for the Clinical Progression to AIDS among HIV-1 Virus Controllers in a Mixed Population of the Amazon Region of Brazil.International journal of molecular sciences · 2023Article
- Ongoing HIV-1 evolution and reservoir reseeding in two elite controllers with genetically diverse peripheral proviral quasispecies.Memorias do Instituto Oswaldo Cruz · 2023Article
- HIV-1 elite controllers: an immunovirological review and clinical perspectives.Journal of virus eradication · 2019Article
- Current Treatment Options for HIV Elite Controllers: a Review.Current treatment options in infectious diseases · 2018Article
- Plasmatic Levels of IL-18, IP-10, and Activated CD8Frontiers in immunology · 2018Article
- Observational
- Effect of the Latent Reservoir on the Evolution of HIV at the Within- and Between-Host Levels.PLoS computational biology · 2017Article
- Proinflammatory isoforms of IL-32 as novel and robust biomarkers for control failure in HIV-infected slow progressors.Scientific reports · 2016Article
- Normal T-cell activation in elite controllers with preserved CD4+ T-cell counts.AIDS (London, England) · 2015Article
- Hospitalization Rates and Reasons Among HIV Elite Controllers and Persons With Medically Controlled HIV Infection.The Journal of infectious diseases · 2015Article
- Clinical outcomes and antiretroviral therapy in 'elite' controllers: a review of the literature.Journal of virus eradication · 2015Article
- HIV controllers with different viral load cutoff levels have distinct virologic and immunologic profiles.Journal of acquired immune deficiency syndromes (1999) · 2015Article
- A Human Immunodeficiency Virus Controller With a Large Population of CD4(+)CD8(+) Double-Positive T Cells.Open forum infectious diseases · 2015Article
- Immunologic and Virologic Progression in HIV Controllers: The Role of Viral "Blips" and Immune Activation in the ANRS CO21 CODEX Study.PloS one · 2015Article
- Candida esophagitis in a human immunodeficiency virus-1-positive elite controller with hepatitis C virus cirrhosis.Open forum infectious diseases · 2014Article
- Long-term control of viral replication in a Group O, human immunodeficiency virus type 1-infected individual.AIDS research and human retroviruses · 2014Article
- Effect of antiretroviral therapy on HIV reservoirs in elite controllers.The Journal of infectious diseases · 2013Article
Corrections and comments
- Commented on by
Authors and funding
6 authors.
Funding
Abstract
Elite controllers or suppressors are untreated human immunodeficiency virus type 1 (HIV-1)-infected patients who maintain undetectable viral loads. In this study, we show that most elite suppressors do not experience significant changes in T cell counts over a 10-year period. Interestingly, treatment of an elite suppressor with highly active antiretroviral therapy (HAART) led to a marked decrease in immune activation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.