ArticleClinical research in cardiology : official journal of the German Cardiac Society2009
Gender differences in patients with acute ST-elevation myocardial infarction complicated by cardiogenic shock.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis.Critical care (London, England) · 2024Pooled it
- Gender differences in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Trial
- Sex disparities in revascularization strategies and mortality in infarct-related cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Evaluating gender-based disparities in the outcomes of impella use in acute myocardial infarction patients with cardiogenic shock; insights from real-world global data.BMC cardiovascular disorders · 2025Article
- Sex-specific outcomes in acute myocardial infarction-associated cardiogenic shock treated with and without V-A ECMO: a retrospective German nationwide analysis from 2014 to 2018.Heart and vessels · 2025Article
- Article
- Sex differences in acute cardiovascular care: a review and needs assessment.Cardiovascular research · 2022Review
- Activation of PPCI team in the octogenarian and nonagenarians population: real-world single-centre experience.Open heart · 2021Observational
- Cardiogenic shock in the setting of acute myocardial infarction: Another area of sex disparity?World journal of cardiology · 2021Review
- Gender disparities with the use of percutaneous left ventricular assist device in patients undergoing percutaneous coronary intervention complicated by cardiogenic shock: From pVAD Working Group.Indian heart journal · 2018Article
- Gender Disparities in Presentation, Management, and Outcomes of Acute Myocardial Infarction.Current cardiology reports · 2018Review
- Prognostic Analysis for Cardiogenic Shock in Patients with Acute Myocardial Infarction Receiving Percutaneous Coronary Intervention.BioMed research international · 2017Article
- Gender Related Survival Differences in ST-Elevation Myocardial Infarction Patients Treated with Primary PCI.International journal of medical sciences · 2016Article
- Gender differences in therapeutic recommendation after diagnostic coronary angiography: insights from the Coronary Angiography and PCI Registry of the German Society of Cardiology.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Sex differences in porcine left ventricular myocardial remodeling due to right ventricular pacing.Biology of sex differences · 2015Article
- Have we given up on intra-aortic balloon counterpulsation in post-myocardial infarction cardiogenic shock?Clinical cardiology · 2013Article
- Age-dependent differences in diabetes and acute hyperglycemia between men and women with ST-elevation myocardial infarction: a cohort study.Diabetology & metabolic syndrome · 2013Article
- Mortality in a cardiac intensive care unit.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- Gender's impact on outcome in coronary surgery with minimized extracorporeal circulation.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- Gender-related differences in patients with ST-elevation myocardial infarction: results from the registry study of the ST elevation myocardial infarction network Essen.Clinical cardiology · 2011Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of our analysis is to assess gender differences in baseline characteristics, acute therapies, and clinical outcome in patients with acute ST-elevation myocardial infarction (STEMI) complicated by cardiogenic shock.
methodsThe Maximal Individual Therapy of Acute Myocardial Infarction PLUS registry (MITRA PLUS) is a German prospective, multicenter, observational data pool of current treatment of STEMI.
resultsSTEMI was more often (P < 0.0001) complicated by cardiogenic shock in female patients (12.9%) when compared to male patients (9.3%). This was still true after adjusting for confounding variables (OR 1.19, 95% CI 1.09-1.30). Women with STEMI admitted in a cardiogenic shock were older (P < 0.0001) and had more often concomitant diseases (P < 0.0001). There was no differences in rates of reperfusion therapy (OR 0.92, 95% CI 0.77-1.09). Hospital mortality was 67.7% in female patients, when compared to 57.2% in male patients (P < 0.0001). After adjusting for confounding variables in the multivariate analysis hospital mortality did not differ between men and women (OR 1.16, 95% CI 0.98-1.38). Early reperfusion therapy was associated with a significant reduction of hospital mortality in female patients with STEMI complicated by cardiogenic shock (OR 0.68, 95% CI 0.52-0.90) with primary PCI being more effective than thrombolytic therapy (OR 0.46, 95% CI 0.31-0.68).
conclusionIn women, STEMI was more often complicated by cardiogenic shock when compared to men. However, the use of early reperfusion therapy did not differ between the sexes. Primary PCI was associated with the best outcome in female patients with STEMI complicated by cardiogenic shock and is therefore the therapy of choice.
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