ReviewPLoS computational biology2009
The role of medical structural genomics in discovering new drugs for infectious diseases.
Review in PLoS computational biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The Difficult Path to the Discovery of Novel Treatments in Psychiatric Disorders.Advances in neurobiology · 2023Article
- Recent Advances in Genomics-Based Approaches for the Development of Intracellular Bacterial Pathogen Vaccines.Pharmaceutics · 2022Review
- Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx.Acta crystallographica. Section F, Structural biology communications · 2022Article
- Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.Scientific reports · 2017Article
- Low potency toxins reveal dense interaction networks in metabolism.BMC systems biology · 2016Article
- Structural and Functional Highlights of Vacuolar Soluble Protein 1 from Pathogen Trypanosoma brucei brucei.The Journal of biological chemistry · 2015Article
- Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia.Acta crystallographica. Section D, Biological crystallography · 2012Article
- Structural genomics of infectious disease drug targets: the SSGCID.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011Article
- The Protein Maker: an automated system for high-throughput parallel purification.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011Article
- Structures of a putative ζ-class glutathione S-transferase from the pathogenic fungus Coccidioides immitis.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011Article
- Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.Acta crystallographica. Section F, Structural biology and crystallization communications · 2011Article
- Microbial genomics and infectious diseases.The New England journal of medicine · 2011Review
- SAD phasing using iodide ions in a high-throughput structural genomics environment.Journal of structural and functional genomics · 2011Article
- Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.Journal of structural and functional genomics · 2011Article
- Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.Molecular and biochemical parasitology · 2011Article
- Toward prediction of functional protein pockets using blind docking and pocket search algorithms.Protein science : a publication of the Protein Society · 2011Article
- Crystal structure of Toxoplasma gondii porphobilinogen synthase: insights on octameric structure and porphobilinogen formation.The Journal of biological chemistry · 2011Article
- Fragment screening of infectious disease targets in a structural genomics environment.Methods in enzymology · 2011Article
- Unmet challenges of structural genomics.Current opinion in structural biology · 2010Review
- Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.