Evidence map›Paper›PMID 19855817›Full record

ReviewPLoS pathogens2009

The application of genomics to emerging zoonotic viral diseases.

Bart L Haagmans, Arno C Andeweg, Albert D M E Osterhaus

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Pathogenic viruses: Molecular detection and characterization.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Review
  2. Prediction of cross-species infection propensities of viruses with receptor similarity.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Polar profile of antiviral peptides from AVPpred Database.Cell biochemistry and biophysics · 2014
    Article
  9. Role of genomic and proteomic tools in the study of host-virus interactions and virus evolution.Indian journal of virology : an official organ of Indian Virological Society · 2013
    Article
  10. Article
  11. Virus discovery: one step beyond.Current opinion in virology · 2013
    Article
  12. 6th International Conference on Emerging Zoonoses.Zoonoses and public health · 2012
    Article
  13. Review
  14. Viral quasispecies evolution.Microbiology and molecular biology reviews : MMBR · 2012
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bart L HaagmansDepartment of Virology, Erasmus Medical Center, Rotterdam, The Netherlands.
Arno C Andeweg
Albert D M E Osterhaus

Funding

Macaque Model and Gene Expression Profiling of SARSR01HL080621 · NHLBI · UNIVERSITY OF WASHINGTON · PI KATZE, MICHAEL G · 2006 to 2009
$2.5M
NHLBI NIH HHS R01 HL080621NHLBI NIH HHS R01 HL080621-O1A1
6 · The paper itself

Abstract

Interspecies transmission of pathogens may result in the emergence of new infectious diseases in humans as well as in domestic and wild animals. Genomics tools such as high-throughput sequencing, mRNA expression profiling, and microarray-based analysis of single nucleotide polymorphisms are providing unprecedented ways to analyze the diversity of the genomes of emerging pathogens as well as the molecular basis of the host response to them. By comparing and contrasting the outcomes of an emerging infection with those of closely related pathogens in different but related host species, we can further delineate the various host pathways determining the outcome of zoonotic transmission and adaptation to the newly invaded species. The ultimate challenge is to link pathogen and host genomics data with biological outcomes of zoonotic transmission and to translate the integrated data into novel intervention strategies that eventually will allow the effective control of newly emerging infectious diseases.

Indexed as

ZoonosesAnimalsCommunicable Diseases, EmergingGenomicsHumansInfluenza A virusInfluenza, HumanOrthomyxoviridae InfectionsSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirus

Identifiers

PMID19855817
PMCPMC2734983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.