ArticleAnnals of surgery1991
Risks of intestinal anastomoses in Crohn's disease.
Article in Annals of surgery, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 202 citations in OpenAlex.
- Comparing outcomes between side-to-side anastomosis and other anastomotic configurations after intestinal resection for patients with Crohn's disease: a meta-analysis.World journal of surgery · 2013Pooled it
- Treatment of the anastomotic complications in patients with Crohn's disease.International journal of colorectal disease · 2011Trial
- Patients at high risk of postoperative complications in Crohn's disease: a meta-analysis and systematic review.Archives of medical science : AMS · 2026Review
- The Relationship between the Psoas Muscle Mass Index and Postoperative Complications in Crohn's Disease: A Retrospective Cohort Study.Journal of the anus, rectum and colon · 2025Article
- Outcomes after right-sided colon surgery in Crohn's disease versus cancer.Techniques in coloproctology · 2024Article
- Comparison of Post-Operative Outcomes of Right Colectomy between Crohn's Disease and Adenocarcinoma of the Right Colon: A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- Percutaneous Drainage vs. Surgery as Definitive Treatment for Anastomotic Leak after Intestinal Resection in Patients with Crohn's Disease.Journal of clinical medicine · 2023Article
- Anastomotic Considerations in Crohn's Disease.Clinics in colon and rectal surgery · 2023Review
- Effect of immunosuppressive medication on postoperative complications following abdominal surgery in Crohn's disease patients.International journal of colorectal disease · 2022Article
- It is not NOD2 - genetic and clinical risk factors for postoperative complications following ileocolic resection in Crohn's disease.International journal of colorectal disease · 2022Article
- Late is too late? Surgical timing and postoperative complications after primary ileocolic resection for Crohn's disease.International journal of colorectal disease · 2022Article
- Surgical Planning in Penetrating Abdominal Crohn's Disease.Frontiers in surgery · 2022Review
- Advantages and disadvantages of corticosteroid use for acute exacerbation of interstitial pneumonia after pulmonary resection.General thoracic and cardiovascular surgery · 2021Article
- Article
- Hypoalbuminaemia and Postoperative Outcomes in Inflammatory Bowel Disease: the NSQIP Surgical Cohort.Journal of Crohn's & colitis · 2019Article
- Surgical outcomes of patients treated with ustekinumab vs. vedolizumab in inflammatory bowel disease: a matched case analysis.International journal of colorectal disease · 2019Article
- Risk factors for early postoperative complications and length of hospital stay in ileocecal resection and right hemicolectomy for Crohn's disease: a single-center experience.International journal of colorectal disease · 2018Article
- Validation and optimization of the Systemic Inflammation-Based modified Glasgow Prognostic Score in predicting postoperative outcome of inflammatory bowel disease: preliminary data.Scientific reports · 2018Article
- Preoperative hypoalbuminemia is associated with an increased risk for intra-abdominal septic complications after primary anastomosis for Crohn's disease.Gastroenterology report · 2017Article
- Correlation Between Anastomotic Configuration and Long-term Outcomes in Surgery for Crohn Disease.Annals of coloproctology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Six hundred fifty-eight intestinal anastomoses in 429 operations for Crohn's disease were studied prospectively during an 8-year period to detect variables connected with perioperative morbidity. Postoperative complications occurred in 9.7% of the patients, 4% had to be reoperated on, and the overall mortality rate was 0.5%. In multivariate analysis by stepwise logistic regression, the only variable significantly (p = 0.03) associated with overall rate of complications was long-term corticosteroid therapy. Serious complications were more common in cases of intra-abdominal abscesses (p = 0.01) and preoperative steroid medication (p = 0.03). The combination of both of these risk factors increased the rate of reoperations from 0.6% (no steroids, no abscess) to 16% (steroids and abscess). No significant association with postoperative complications could be found for age, sex, duration of disease, previous operations, nutritional status, emergency surgery, extent of disease, type, number, and localization of anastomoses, presence of proximal ileo-/colostomy, or histologically inflamed margins of resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.