SynthesisPsychosomatics
Cancer-related fatigue and its associations with depression and anxiety: a systematic review.
Synthesis in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
150 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Prevalence, severity, and risk factors of cancer-related fatigue among working cancer survivors: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2025Pooled it
- Yoga for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025Pooled it
- Exercise to Manage Fatigue During and After Chemotherapy in Adolescents and Young Adults With Cancer: A Systematic Review and Meta-Analysis.Oncology nursing forum · 2025Pooled it
- Cardiovascular training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025Pooled it
- Resistance training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2024Pooled it
- Barriers and facilitators to physical activity participation for child, adolescent, and young adult cancer survivors: a systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Bibliometric and visualization analyses of cancer-related fatigue research published worldwide from 2001 to 2023.Frontiers in oncology · 2024Pooled it
- Risk factors for cancer-related fatigue in patients with colorectal cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Employment and Work Ability of Persons With Brain Tumors: A Systematic Review.Frontiers in human neuroscience · 2020Pooled it
- Validated Screening Tools for Common Mental Disorders in Low and Middle Income Countries: A Systematic Review.PloS one · 2016Pooled it
- Acupuncture for cancer-related fatigue: a systematic review of randomized clinical trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Pooled it
- The Effectiveness of Immersive Virtual Reality as A Complementary Approach and a New Direction in Cancer Related Fatigue Management.Integrative cancer therapiesPooled it
- The Effects of Acupuncture on Cancer-Related Fatigue: Updated Systematic Review and Meta-Analysis.Integrative cancer therapiesPooled it
- Music Therapy Versus Cognitive Behavioral Therapy via Telehealth for Anxiety in Survivors of Cancer: A Randomized Clinical Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026Trial
- Trial
- Factors associated with significant improvement in cancer-related fatigue after completing cognitive behavioral therapy for insomnia in cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Trial
- Trial
- Prevalence, Severity, and Co-Occurrence of SPPADE Symptoms in 31,866 Patients With Cancer.Journal of pain and symptom management · 2023Trial
- Relationship between social support, physical symptoms, and depression in women with breast cancer and pain.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Managing Anxiety from Cancer (MAC): A pilot randomized controlled trial of an anxiety intervention for older adults with cancer and their caregivers.Palliative & supportive care · 2021Trial
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundFatigue is an important symptom in cancer and has been shown to be associated with psychological distress.
objectiveThis review assesses evidence regarding associations of cancer-related fatigue with depression and anxiety.
methodDatabase searches yielded 59 studies reporting correlation coefficients or odds ratios.
resultsThe combined sample size was 12,103. Almost all studies showed a correlation of fatigue with depression and with anxiety. However, 31 different instruments were used to assess fatigue, suggesting a lack of consensus on measurement.
conclusionThis review confirms the association of fatigue with depression and anxiety. Directionality needs to be better delineated in longitudinal studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.