Evidence map›Paper›PMID 19852504›Full record

ArticleThe Journal of organic chemistry2009

Multi-gram scale synthesis of FR180204.

Samarjit Patnaik, Harry C Dietz, Wei Zheng, Christopher Austin, Juan J Marugan

Open access · greenAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Other targeted drugs in melanoma.Annals of translational medicine · 2015
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samarjit PatnaikNational Institutes of Health Chemical Genomics Center, 9800 Medical Center Drive, Rockville, Maryland 20850, USA. patnaiks@mail.nih.gov
Harry C Dietz
Wei Zheng
Christopher Austin
Juan J Marugan
National Institutes of Health · USJohns Hopkins University · US

Funding

NIH Chemical Genomics CenterZIBHG200319 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI AUSTIN, CHRISTOPHER P · 2010 to 2011
$55.9M
Intramural NIH HHS Z99 HG999999
6 · The paper itself

Abstract

A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

Indexed as

Molecular StructurePyrazolesPyridazinesStereoisomerismFR 180204PyrazolesPyridazines

Identifiers

PMID19852504
PMCPMC2862695
OpenAlexW2041183231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.