Evidence map›Paper›PMID 19851750›Full record

ArticleDer Orthopade2009

[Tissue engineering of cartilage and bone : growth factors and signaling molecules].

C Brochhausen, M Lehmann, R Zehbe, B Watzer, S Grad, A Meurer, C J Kirkpatrick

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Orthopade, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Effect of essential oil of Rosa Damascena on human colon cancer cell line SW742.Gastroenterology and hepatology from bed to bench · 2013
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

C BrochhausenREPAIR-lab, Institut für Pathologie, Universitätsmedizin, Johannes Gutenberg-Universität, Langenbeckstrasse 1, 55101, Mainz, Deutschland. brochhausen@pathologie.klinik.uni-mainz.de
M Lehmann
R Zehbe
B Watzer
S Grad
A Meurer
C J Kirkpatrick
Johannes Gutenberg University Mainz · DEAO Foundation · CHGoethe University Frankfurt · DEPhilipps University of Marburg · DETechnische Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern tissue engineering concepts integrate cells, scaffolds, signaling molecules and growth factors. In tissue engineering of cartilage, the growth plate of the long bone represents an interesting, well-organized developmental structure, with a spatial distribution of chondrocytes in different proliferation and differentiation stages embedded in a scaffold of extracellular matrix components. The proliferation and differentiation of these chondrocytes is regulated by various hormonal and paracrine factors. This article discusses some important growth factors in the process of endochondral ossification and demonstrates how this information could be translated into a controlled release system for different tissue engineering strategies.

Indexed as

AnimalsBone and BonesCartilageCell DifferentiationChondrocytesExtracellular Matrix ProteinsGuided Tissue RegenerationHumansIntercellular Signaling Peptides and ProteinsTissue EngineeringTissue ScaffoldsExtracellular Matrix ProteinsIntercellular Signaling Peptides and Proteins

Identifiers

PMID19851750
OpenAlexW1603474166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.