ArticleJournal of microbiology (Seoul, Korea)2009
Evidence against the physiological role of acetyl phosphate in the phosphorylation of the ArcA response regulator in Escherichia coli.
Article in Journal of microbiology (Seoul, Korea), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- ArcA modulates multidrug resistance and compound susceptibility inMicrobiology spectrum · 2025Article
- Article
- The ArcAB Two-Component System: Function in Metabolism, Redox Control, and Infection.Microbiology and molecular biology reviews : MMBR · 2022Review
- Identification of Z nucleotides as an ancient signal for two-component system activation in bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Acetate and Potassium Modulate the Stationary-Phase Activation ofFrontiers in microbiology · 2020Article
- Electrochemically active bacteria sense electrode potentials for regulating catabolic pathways.Nature communications · 2018Article
- Effects of the global regulator CsrA on the BarA/UvrY two-component signaling system.Journal of bacteriology · 2015Article
- Acetyl-Phosphate Is Not a Global Regulatory Bridge between Virulence and Central Metabolism in Borrelia burgdorferi.PloS one · 2015Article
- Metabolic Engineering of Escherichia coli for Production of Mixed-Acid Fermentation End Products.Frontiers in bioengineering and biotechnology · 2014Review
- Probing the ArcA regulon in the rumen bacterium Mannheimia succiniciproducens by genome-wide expression profiling.Journal of microbiology (Seoul, Korea) · 2012Article
- ArcS, the cognate sensor kinase in an atypical Arc system of Shewanella oneidensis MR-1.Applied and environmental microbiology · 2010Article
- The physiological stimulus for the BarA sensor kinase.Journal of bacteriology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arc two-component signal transduction system of Escherichia coli comprises the ArcB sensor kinase and the ArcA response regulator. Under anoxic growth conditions, ArcB autophosphorylates and transphos-phorylates ArcA, which, in turn, represses or activates its target operons. ArcA has been shown to be able to autophosphorylate in vitro at the expense of acetyl-P. Here, the in vivo effect of acetyl phosphate on the redox signal transduction by the Arc system was assessed. Our results indicate that acetyl phosphate can modulate the expression of ArcA-P target genes only in the absence of ArcB. Therefore, the acetyl phosphate dependent ArcA phosphorylation route does not seem to play a significant role under physiological conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.