Evidence map›Paper›PMID 19850723›Full record

ArticleNucleic acids research2010

The IntAct molecular interaction database in 2010.

B Aranda, P Achuthan, Y Alam-Faruque, I Armean, A Bridge, C Derow, M Feuermann, A T Ghanbarian, S Kerrien, J Khadake and 11 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 358 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
358citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

358 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genetic and environmental risk factors for dementia in African adults: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Article
  3. Review
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  5. Mapping the influence of hydrocarbons mixture on molecular mechanisms, involved in breast and lung neoplasms: in silico toxicogenomic data-mining.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2024
    Article
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  9. Building Protein-Protein Interaction Graph Database Using Neo4j.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. PRO-Simat: Protein network simulation and design tool.Computational and structural biotechnology journal · 2023
    Article
  11. Article
  12. Prediction and Ranking of Biomarkers UsingInternational journal of molecular sciences · 2022
    Article
  13. Structure and dynamics of membrane protein in SARS-CoV-2.Journal of biomolecular structure & dynamics · 2022
    Article
  14. Article
  15. Article
  16. An overview of graph databases and their applications in the biomedical domain.Database : the journal of biological databases and curation · 2021
    Article
  17. Genome analyses of 174 strains ofMicrobial genomics · 2021
    Article
  18. Article
  19. Article
  20. Article

298 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

B ArandaEMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus Hinxton, Cambridge CB10 1SD, UK.
P Achuthan
Y Alam-Faruque
I Armean
A Bridge
C Derow
M Feuermann
A T Ghanbarian
S Kerrien
J Khadake
J Kerssemakers
C Leroy
M Menden
M Michaut
L Montecchi-Palazzi
S N Neuhauser
S Orchard
V Perreau
B Roechert
K van Eijk
H Hermjakob

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntAct is an open-source, open data molecular interaction database and toolkit. Data is abstracted from the literature or from direct data depositions by expert curators following a deep annotation model providing a high level of detail. As of September 2009, IntAct contains over 200.000 curated binary interaction evidences. In response to the growing data volume and user requests, IntAct now provides a two-tiered view of the interaction data. The search interface allows the user to iteratively develop complex queries, exploiting the detailed annotation with hierarchical controlled vocabularies. Results are provided at any stage in a simplified, tabular view. Specialized views then allows 'zooming in' on the full annotation of interactions, interactors and their properties. IntAct source code and data are freely available at http://www.ebi.ac.uk/intact.

Indexed as

Databases, GeneticDatabases, ProteinAnimalsComputational BiologyFalse Positive ReactionsHumansInformation Storage and RetrievalInternetProgramming LanguagesProtein Interaction MappingProteinsProtein Structure, TertiarySoftwareUser-Computer InterfaceVocabulary, ControlledProteins

Identifiers

PMID19850723
PMCPMC2808934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.