Evidence map›Paper›PMID 19849827›Full record

ReviewCritical care (London, England)2009

Health technology assessment review: Computerized glucose regulation in the intensive care unit--how to create artificial control.

Miriam Hoekstra, Mathijs Vogelzang, Evgeny Verbitskiy, Maarten W N Nijsten

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01085071 (GRIP-COMPASS Trial), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01085071 phase4completednot on this map

GRIP-COMPASS Trial: Computer-driven Glucose and Potassium Regulation Program in Intensive Care Patients With COMparison of PotASSium Targets Within normokAlemic Range

TypeinterventionalSponsorUniversity Medical Center GroningenRan2009 to 2012Enrolled1,225ConditionsThoracic Surgery, Cardiac Surgery, Critically IllArmsPotassium Chloride
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Continuous Insulin Infusion: When, Where, and How?Diabetes spectrum : a publication of the American Diabetes Association · 2014
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miriam HoekstraDepartments of Anesthesiology and Cardiology, University Medical Center Groningen, 9700 RB Groningen, the Netherlands. m.hoekstra@thorax.umcg.nl
Mathijs Vogelzang
Evgeny Verbitskiy
Maarten W N Nijsten

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current care guidelines recommend glucose control (GC) in critically ill patients. To achieve GC, many ICUs have implemented a (nurse-based) protocol on paper. However, such protocols are often complex, time-consuming, and can cause iatrogenic hypoglycemia. Computerized glucose regulation protocols may improve patient safety, efficiency, and nurse compliance. Such computerized clinical decision support systems (Cuss) use more complex logic to provide an insulin infusion rate based on previous blood glucose levels and other parameters. A computerized CDSS for glucose control has the potential to reduce overall workload, reduce the chance of human cognitive failure, and improve glucose control. Several computer-assisted glucose regulation programs have been published recently. In order of increasing complexity, the three main types of algorithms used are computerized flowcharts, Proportional-Integral-Derivative (PID), and Model Predictive Control (MPC). PID is essentially a closed-loop feedback system, whereas MPC models the behavior of glucose and insulin in ICU patients. Although the best approach has not yet been determined, it should be noted that PID controllers are generally thought to be more robust than MPC systems. The computerized Cuss that are most likely to emerge are those that are fully a part of the routine workflow, use patient-specific characteristics and apply variable sampling intervals.

Indexed as

Decision Support Systems, ClinicalIntensive Care UnitsBlood GlucoseGlycemic IndexHumansHyperglycemiaHypoglycemiaQuality of Health CareTherapy, Computer-AssistedBlood Glucose

Identifiers

PMID19849827
PMCPMC2784347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.