Evidence map›Paper›PMID 19849816›Full record

ReviewArthritis research & therapy2009

Genetics of rheumatic disease.

Alex Clarke, Timothy J Vyse

Open access · goldAbstract readReview
In one paragraph

Review in Arthritis research & therapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Influence ofMediators of inflammation · 2018
    Article
  6. Article
  7. Article
  8. Feline degenerative joint disease: a genomic and proteomic approach.Journal of feline medicine and surgery · 2013
    Article
  9. Article
  10. Article
  11. Cytokines as therapeutic targets in SLE.Nature reviews. Rheumatology · 2010
    Review
  12. Article
  13. The autoimmune tautology.Arthritis research & therapy · 2010
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alex ClarkeImperial College London, Faculty of Medicine, Section of Molecular Genetics and Rheumatology, Fifth Floor, Commonwealth Building, Hammersmith Hospital, London W12 0NN, UK. alex@actualmedia.com
Timothy J Vyse
Hammersmith Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many of the chronic inflammatory and degenerative disorders that present to clinical rheumatologists have a complex genetic aetiology. Over the past decade a dramatic improvement in technology and methodology has accelerated the pace of gene discovery in complex disorders in an exponential fashion. In this review, we focus on rheumatoid arthritis, systemic lupus erythematosus and ankylosing spondylitis and describe some of the recently described genes that underlie these conditions and the extent to which they overlap. The next decade will witness a full account of the main disease susceptibility genes in these diseases and progress in establishing the molecular basis by which genetic variation contributes to pathogenesis.

Indexed as

AnimalsGenetic Predisposition to DiseaseHumansRheumatic Diseases

Identifiers

PMID19849816
PMCPMC2787281
OpenAlexW2079995796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.