ArticleDrugs & aging2009
Medication-related admissions in older people: a cross-sectional, observational study.
Article in Drugs & aging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01223950 (Monitoring the Prevalence of E.R Admissions and Hospitalizations as a Result of Drug Related Problems), which is not on this map. Cited by 27 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitoring the Prevalence of E.R Admissions and Hospitalizations as a Result of Drug Related Problems (DRPs)
Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Hospital admissions due to adverse drug reactions in the elderly. A meta-analysis.European journal of clinical pharmacology · 2017Pooled it
- A systematic review of hospitalization resulting from medicine-related problems in adult patients.British journal of clinical pharmacology · 2014Pooled it
- Identifying high-risk medication: a systematic literature review.European journal of clinical pharmacology · 2014Pooled it
- Drug-Related Hospital Visits and Admissions Associated with Laboratory or Physiologic Abnormalities-A Systematic-Review.PloS one · 2013Pooled it
- Methods for assessing the preventability of adverse drug events: a systematic review.Drug safety · 2012Pooled it
- Antipsychotic prescribing and drug-related readmissions in multimorbid older inpatients: a post-hoc analysis of the OPERAM population.International journal of clinical pharmacy · 2024Trial
- Detectability of Medication Errors With a STOPP/START-Based Medication Review in Older People Prior to a Potentially Preventable Drug-Related Hospital Admission.Drug safety · 2022Trial
- The impact of a medication review with follow-up service on hospital admissions in aged polypharmacy patients.British journal of clinical pharmacology · 2016Trial
- Opti-Med: the effectiveness of optimised clinical medication reviews in older people with 'geriatric giants' in general practice; study protocol of a cluster randomised controlled trial.BMC geriatrics · 2014Trial
- Prevalence and factors associated with preventable drug-related emergency department visits (DREDBMC emergency medicine · 2024Article
- Drug-related hospital admissions in older adults: comparison of the Naranjo algorithm and an adjusted version of the Kramer algorithm.European geriatric medicine · 2022Article
- Drug-Related Hospital AdmissionsFrontiers in pharmacology · 2022Article
- Adverse drug events leading to emergency department visits: A multicenter observational study in Korea.PloS one · 2022Observational
- Hospital admissions to geriatric ward related to adverse drug events: a cross-sectional study from the Czech Republic.International journal of clinical pharmacy · 2021Article
- Efficiency versus thoroughness in medication review: a qualitative interview study in UK primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Assessment tool for hospital admissions related to medications: development and validation in older patients.International journal of clinical pharmacy · 2019Article
- Trends in polypharmacy and dispensed drugs among adults in the Netherlands as compared to the United States.PloS one · 2019Article
- Changes in medicine prescription following a medication review in older high-risk patients with polypharmacy.International journal of clinical pharmacy · 2018Article
- Is polypharmacy an independent risk factor for adverse outcomes after an emergency department visit?Internal and emergency medicine · 2017Observational
- [Adverse drug reactions in elderly people : First data from the Leipzig Research Center for Civilization Diseases (LIFE)].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMedication-related admissions are an important cause of hospital admissions in older people. The scope for prevention is less clear.
objectivesTo characterize medication-related hospital admissions in older people and assess their preventability.
methodsThis was a cross-sectional, observational study conducted over 3 months. A pharmacist based in the medical admissions ward of a north London hospital screened all patients aged > or =65 years. A specialist physician assembled additional information, which was presented to a multi-professional panel to confirm attribution and preventability. A total of 409 patients were screened, of whom 14% (95% CI 10.6, 17.4) had medication-related problems, 6.4% (95% CI 4.0, 8.8) were admitted because of medication-related problems and 3.9% (95% CI 2.0, 5.8) were considered to have preventable medication-related problems. Medicines to prevent or treat cardiovascular disease were implicated in 69% (18/26) of the medication-related admissions and 69% (11/16) of preventable medication-related admissions. Amongst hospitalized patients, admission attributed to adverse drug reaction was more likely as the number of medications being taken increased, and admission attributed to undertreatment was more likely as the number of pre-existing conditions increased.
conclusionMedication-related admissions are common in older people and over half are preventable. Morbidity associated with medicines used for cardiovascular disease is important. There is a difficult balance to be struck between avoiding iatrogenic illness in older people and ensuring they benefit from medications for pre-existing conditions. Opportunities exist for improving the delivery of care to reduce adverse outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.